A team in Spain used enhanced primer design, magnetic separation, and electrochemical detection to build a TB test as specific and sensitive as PCR.
The firm is using CMOS technology to develop a rapid TB test and other infectious disease panels, and is also partnering with other companies to enable tests.
In Nature this week: researchers uncover 13 healthy people who harbor Mendelian disease mutations, new tree of life, and more.
Researchers discussed using WGS to predict antibacterial resistance, to inform influenza vaccine development, and to diagnose and build drug resistance profiles for tuberculosis.
An international research team has mined tuberculosis whole-genome datasets to identify new mechanisms of resistance to highly toxic drugs.
The study describes an RNA expression signature unique to people who are likely to develop an active TB infection, which could help prevent it.
In PLOS this week: sites in dog genome under selection during early domestication, tuberculosis transmission patterns, and more.
A genome-wide association study of HIV-infected individuals in Uganda and Tanzania led to a chromosome 5 locus that may protect against active TB infection.
Researchers used existing expression data for thousands of individuals, including those with active and latent TB, to find a three-gene signature for active infection.
In PLOS this week: researchers explore the transfer of host genetic material into viruses, and more.
The Washington Post reports that a Russian Academy of Sciences commission has led to the retraction of hundreds of scientific papers.
The Los Angeles Times' Daily Pilot reports the chief executive of Vantari Genetics has pleaded guilty in a kickback scheme.
News 4 Jax reports that a Florida bill to prevent life and long-term care insurers from using genetic information in their coverage decisions has easily passed one committee.
In Science this week: potentially pathogenic mutations found in hematopoietic stem cells from young healthy donors, and more.