The research team evaluated the Illumina MiSeq and Ion PGM sequencing platforms, as well as the bioinformatics pipelines TBProfiler and Mykrobe predictor.
In PLOS this week: genetic evolution of Mycobacterium tuberculosis, mutation rate variation patterns in people, and more.
The evidence-based guidelines for testing individuals at risk of latent or active TB infection include recommendations on interferon-gamma release and molecular assays.
The company has identified markers of latent disease that it is now investigating to see if they could be useful for predicting progression to active infection.
The funding will be used to further develop a 20-minute tuberculosis detection assay and drug susceptibility test using the firm's handheld Q-POC microfluidic PCR system.
In PNAS this week: effect of structural variants on gene expression in cancer, Mycobacterium tuberculosis population genomics study, and more.
Cepheid noted that the cartridge is not currently part of its five-year commercial plan, but the firm is in discussions with outside parties to push development forward.
Sequencing on post-mortem samples from individuals infected with Mycobacterium tuberculosis and HIV revealed diversification and spread of the TB pathogen in the body.
Synlab, a European lab services provider, found the test performed well on samples with low bacterial load and non-respiratory samples.
Translational scientist Jacqueline Achkar of Albert Einstein Medical College will lead several collaborations to build a point-of-care diagnostic platform.
Researchers have sequenced the genome of the depth-dwelling giant squid.
Chris Collins, a former US representative, has been sentenced to more than two years in prison in an insider trading case involving an Australian biotechnology firm, the New York Times reports.
Prosecutors have charged a former Drexel University professor with theft for allegedly spending federal grant money on adult entertainment and other unrelated expenses, according to the Philadelphia Inquirer.
In PNAS this week: Trypanosoma brucei transcripts, estimate of people at risk of inherited retinal disease, and more.