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Cepheid is now considering adapting TB tests in development to cover the mutations, an executive told GenomeWeb.
Using array data for thousands of individuals, researchers have identified SNPs near the ASAP1 gene that appear to impact susceptibility to tuberculosis infection.
Tests in development for the Alere q include HIV, tuberculosis, and Ebola assays, and it will initially be targeted to low-resource settings in the developing world.
The new clearance allows the use of the Xpert MTB/RIF test, in conjunction with other clinical or laboratory data, to remove patients from respiratory isolation.
The company's molecular detection technology relies on DNA supercoiling and binding target molecules to single-molecule biosensors within a capillary system.
The partners will test TruCulture as a point-of-care blood collection and immune response monitoring method and to stratify patients with latent and active TB.
Using a combination of genotyping and sequencing, an international team traces the history of a Mycobacterium tuberculosis lineage and its links to drug resistance.
With overlapping technologies, some firms pursue parallel human and animal health diagnostics development, but cost constraints and regulatory dynamics differ. Part one of a two-part series.
An RT-qPCR-based assay of antigen-stimulated blood is a possible next-gen approach for latent TB detection, a Cepheid executive noted in an accompanying commentary.
The data repository of tuberculosis drug susceptibility will spur diagnostic assay development; access will be open to partner firms in one year.
A new blood test might be able to detect the presence of some 50 cancers, according to New Scientist.
Undark looks into how coronavirus-related shutdowns are affecting field researchers.
In PNAS this week: strategies to design DNA oligonucleotide probes for bacteria, Vibrio cholerae evolution in Haiti, and more.
NPR reports that graduate students in the US are helping with SARS-CoV-2 testing.