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tuberculosis

In Nature this week: metagenomic study of tuberculosis victims from the 18th century, and more.

Sequencing of DNA isolated from people buried in an 18th century churchyard finds that victims often were infected with more than one strain of Mycobacterium tuberculosis.

The test will be based on the firm's proprietary complementary metal-oxide semiconductor biochip technology.

Sensitivity of GeneXpert MTB/RIF was better than microscopy, but low enough compared to culture to conclude that a negative Xpert result does not rule out TB in children.

Cepheid is now considering adapting TB tests in development to cover the mutations, an executive told GenomeWeb.

Using array data for thousands of individuals, researchers have identified SNPs near the ASAP1 gene that appear to impact susceptibility to tuberculosis infection.

Tests in development for the Alere q include HIV, tuberculosis, and Ebola assays, and it will initially be targeted to low-resource settings in the developing world.

The new clearance allows the use of the Xpert MTB/RIF test, in conjunction with other clinical or laboratory data, to remove patients from respiratory isolation.

The company's molecular detection technology relies on DNA supercoiling and binding target molecules to single-molecule biosensors within a capillary system.

The partners will test TruCulture as a point-of-care blood collection and immune response monitoring method and to stratify patients with latent and active TB.

 

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A study of families explores how children transmit SARS-CoV-2, according to the Associated Press.

US Agricultural Research Service scientists have sequenced the genome of the Asian giant hornet.

According to the Economist, pooled testing for COVID-19 could help alleviate strains on testing labs.

In Science this week: MIT researchers outline approach dubbed translatable components regression to predict treatment response among IBD patients.