A study of more than 700 samples showed pooling detected 96 percent of the tuberculosis cases found via testing each patient sample individually, with 99 percent overall agreement between the methods.
Faster sequencing of Mycobacterium tuberculosis from sputum samples and analysis of resistance genes could enable better disease treatment, the researchers said.
The license was issued to the firm's distribution partner, Xcelris Labs, and Epistem intends to begin placing its Genedrive molecular platforms in the coming months.
The test detects a signature molecular marker upregulated by viable bacteria, and will be useful for pediatric, extrapulmonary, and AIDS-related TB.
In PLOS this week: Mycobacterium tuberculosis pangenome, Venus clam immune transcriptome, and more.
In Nature this week: metagenomic study of tuberculosis victims from the 18th century, and more.
Sequencing of DNA isolated from people buried in an 18th century churchyard finds that victims often were infected with more than one strain of Mycobacterium tuberculosis.
The test will be based on the firm's proprietary complementary metal-oxide semiconductor biochip technology.
Sensitivity of GeneXpert MTB/RIF was better than microscopy, but low enough compared to culture to conclude that a negative Xpert result does not rule out TB in children.
Cepheid is now considering adapting TB tests in development to cover the mutations, an executive told GenomeWeb.
The New York City Police Department will be removing DNA profiles from a local database if they are from people who were never convicted of a crime, the New York Times reports.
Science reports that accusations of sexual assault against a microbiome researcher has also led to questions about his academic certifications.
Wired reports that researchers are analyzing the DNA fish leave behind in water to study their populations.
In Science this week: comprehensive cellular map of the human thymus, evidence of admixture between the ancestors of Neanderthals and Denisovan and a 'superarchaic' population.