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tuberculosis

In PNAS this week: human cytomegalovirus diversity, patterns of homologous recombination in E. coli, and more.

Intended for diagnosing active pulmonary tuberculosis, the test will use Cere's Nanotrap reagents for enriching target analytes for downstream analysis.

In PLOS this week: genomic analysis of Malaysian tuberculosis strain, database of bat genomes, and more.

Researchers combined genome sequences and drug susceptibility data for thousands of Mycobacterium tuberculosis isolates to find mutations for predicting resistance.

The gift is from a group of more than 20 philanthropists and will be used to develop a rapid diagnostic test for drug-resistant TB. 

A study of more than 700 samples showed pooling detected 96 percent of the tuberculosis cases found via testing each patient sample individually, with 99 percent overall agreement between the methods.

Faster sequencing of Mycobacterium tuberculosis from sputum samples and analysis of resistance genes could enable better disease treatment, the researchers said.

The license was issued to the firm's distribution partner, Xcelris Labs, and Epistem intends to begin placing its Genedrive molecular platforms in the coming months.

The test detects a signature molecular marker upregulated by viable bacteria, and will be useful for pediatric, extrapulmonary, and AIDS-related TB.

In PLOS this week: Mycobacterium tuberculosis pangenome, Venus clam immune transcriptome, and more.

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A study of families explores how children transmit SARS-CoV-2, according to the Associated Press.

US Agricultural Research Service scientists have sequenced the genome of the Asian giant hornet.

According to the Economist, pooled testing for COVID-19 could help alleviate strains on testing labs.

In Science this week: MIT researchers outline approach dubbed translatable components regression to predict treatment response among IBD patients.