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The gift is from a group of more than 20 philanthropists and will be used to develop a rapid diagnostic test for drug-resistant TB.
A study of more than 700 samples showed pooling detected 96 percent of the tuberculosis cases found via testing each patient sample individually, with 99 percent overall agreement between the methods.
Faster sequencing of Mycobacterium tuberculosis from sputum samples and analysis of resistance genes could enable better disease treatment, the researchers said.
The license was issued to the firm's distribution partner, Xcelris Labs, and Epistem intends to begin placing its Genedrive molecular platforms in the coming months.
The test detects a signature molecular marker upregulated by viable bacteria, and will be useful for pediatric, extrapulmonary, and AIDS-related TB.
In PLOS this week: Mycobacterium tuberculosis pangenome, Venus clam immune transcriptome, and more.
In Nature this week: metagenomic study of tuberculosis victims from the 18th century, and more.
Sequencing of DNA isolated from people buried in an 18th century churchyard finds that victims often were infected with more than one strain of Mycobacterium tuberculosis.
The test will be based on the firm's proprietary complementary metal-oxide semiconductor biochip technology.
Sensitivity of GeneXpert MTB/RIF was better than microscopy, but low enough compared to culture to conclude that a negative Xpert result does not rule out TB in children.
A new blood test might be able to detect the presence of some 50 cancers, according to New Scientist.
Undark looks into how coronavirus-related shutdowns are affecting field researchers.
In PNAS this week: strategies to design DNA oligonucleotide probes for bacteria, Vibrio cholerae evolution in Haiti, and more.
NPR reports that graduate students in the US are helping with SARS-CoV-2 testing.