The research team evaluated the Illumina MiSeq and Ion PGM sequencing platforms, as well as the bioinformatics pipelines TBProfiler and Mykrobe predictor.
In PLOS this week: genetic evolution of Mycobacterium tuberculosis, mutation rate variation patterns in people, and more.
The evidence-based guidelines for testing individuals at risk of latent or active TB infection include recommendations on interferon-gamma release and molecular assays.
The company has identified markers of latent disease that it is now investigating to see if they could be useful for predicting progression to active infection.
The funding will be used to further develop a 20-minute tuberculosis detection assay and drug susceptibility test using the firm's handheld Q-POC microfluidic PCR system.
In PNAS this week: effect of structural variants on gene expression in cancer, Mycobacterium tuberculosis population genomics study, and more.
Cepheid noted that the cartridge is not currently part of its five-year commercial plan, but the firm is in discussions with outside parties to push development forward.
Sequencing on post-mortem samples from individuals infected with Mycobacterium tuberculosis and HIV revealed diversification and spread of the TB pathogen in the body.
Synlab, a European lab services provider, found the test performed well on samples with low bacterial load and non-respiratory samples.
Translational scientist Jacqueline Achkar of Albert Einstein Medical College will lead several collaborations to build a point-of-care diagnostic platform.
In PNAS this week: carbapenem resistance in Enterobacteriaceae, selection against educational attainment-linked variants, and more.
Technology Review points out that a new US presidential science advisor hasn't been selected.
Researchers find that blood tests might be able to help determine severity of a concussion, Wired reports.
President-elect Donald Trump considers other candidates for director of the National Institutes of Health, Nature News reports.