transplant rejection

The Boston-based startup wants to help individuals interpret their HLA data for ancestry and health, and participate in research studies. 

Milwaukee, Wis.-based TAI Diagnostics is developing a PCR-based assay for cell-free DNA as a way to monitor the health of transplanted organs.

Investigators characterized expression activity in kidney grafts from a group of transplant recipients who remained rejection-free without immunosuppression.

The researchers plan to evaluate cfDNA and single cells isolated from the urine of patients who have had kidney transplants to identify signs of graft failure.

Piper Jaffray analyst William Quirk said the pricing, which was much higher than expected, will help push CareDx toward profitability.

The final LCD covers AlloSure in renal allograft recipients who have a probability of active renal allograft rejection.

The software provides analysis of HLA typing by NGS on several platforms, including ones from Illumina, Thermo Fisher, and PacBio.

The company said revenues from its non-invasive heart transplant rejection test AlloMap rose about 16 percent year over year.

The researchers plan to work with the NIH's Genome Research Alliance for Transplantation consortium to compare their method with others.

Linkage is now part of Thermo Fisher's transplant diagnostics business, One Lambda. Linkage's flagship product line is its real-time PCR technology, LinkSeq.

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Parabon NanoLabs is partnering with law enforcement to use genetic genealogy approaches to solve cold cases, Buzzfeed News reports.

A Columbia University-led team used emergency contact information from medical records to create family trees and estimate disease heritability.

In Science this week: ancient Southeast Asian genomes provide insight on human migration, and more.

NPR says a new report recommends that former research chimpanzees should be moved to retirement sanctuaries unless that move would shorten their lives.