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testicular cancer

By analyzing more than 100 testicular germ cell tumors, investigators characterized mutation, methylation, and other patterns in four histological subtypes of the disease.

Two new studies have delivered a multitude of new markers linked to testicular cancer, as well as a better understanding of the genetic architecture of the disease.

Exome sequencing data for hundreds of testicular germ cell tumor patients led to the discovery of rare mutations affecting cilia-microtubule genes.

Exome and transcriptome sequences uncovered features that characterized testicular germ cell tumors by whether they did or did not respond to treatment.

Combining the new risk variants with those found in the past, researchers came up with a risk score that may eventually help find those most susceptible to the disease.

NEW YORK (GenomeWeb News) – Two studies appearing in Nature Genetics this week have uncovered about a dozen new loci linked to testicular cancer risk.

NEW YORK (GenomeWeb News) – A subset of non-inherited, early-onset testicular cancer cases involve rare, germline copy number alterations, according to a study appearing online today in the American Journal of Human Genetics.

The American Prospect writes that the pilot program to test the DNA of migrants could lead to more family separations.

An international commission is to develop a report on how researchers, clinicians, and regulators should evaluate the clinical applications of human germline genome editing.

The US Department of Agriculture presents a new blueprint for animal genomic research.

In Genome Research this week: repetitive element deletion linked to altered methylation and more in form of muscular dystrophy; human contamination in draft bacterial and archaeal genomes; and more.