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testicular cancer

European Consortium Seeks to Develop Liquid Biopsy Test for Prostate, Testicular Cancer
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The European Commission awarded a consortium of private companies and academic researchers €759,000 recently to carry out their plans.

Integrated Analyses Offer New Molecular Insights to Testicular Tumor Subtypes

By analyzing more than 100 testicular germ cell tumors, investigators characterized mutation, methylation, and other patterns in four histological subtypes of the disease.

New Testicular Cancer Markers Revealed in Studies

Two new studies have delivered a multitude of new markers linked to testicular cancer, as well as a better understanding of the genetic architecture of the disease.

Some Testicular Cancer Cases Involve Rare Ciliary Gene Mutations

Exome sequencing data for hundreds of testicular germ cell tumor patients led to the discovery of rare mutations affecting cilia-microtubule genes.

Testicular Tumor Genomics Provide Clues to Disease Development, Treatment Resistance

Exome and transcriptome sequences uncovered features that characterized testicular germ cell tumors by whether they did or did not respond to treatment.

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Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.