By analyzing more than 100 testicular germ cell tumors, investigators characterized mutation, methylation, and other patterns in four histological subtypes of the disease.
Two new studies have delivered a multitude of new markers linked to testicular cancer, as well as a better understanding of the genetic architecture of the disease.
Exome sequencing data for hundreds of testicular germ cell tumor patients led to the discovery of rare mutations affecting cilia-microtubule genes.
Exome and transcriptome sequences uncovered features that characterized testicular germ cell tumors by whether they did or did not respond to treatment.
Combining the new risk variants with those found in the past, researchers came up with a risk score that may eventually help find those most susceptible to the disease.
NEW YORK (GenomeWeb News) – Two studies appearing in Nature Genetics this week have uncovered about a dozen new loci linked to testicular cancer risk.
NEW YORK (GenomeWeb News) – A subset of non-inherited, early-onset testicular cancer cases involve rare, germline copy number alterations, according to a study appearing online today in the American Journal of Human Genetics.
The Associated Press reports that gene-edited food may soon be for sale.
The United Nations is to consider a ban on field testing gene drives at a meeting being held next week, Technology Review reports.
The US Department of Health and Human Services is beginning a series of meetings on human fetal tissue research, Stat News reports.
In Cell this week: epigenetic change linked to glioblastomas, rare and low-frequency variants contributing to multiple sclerosis risk, and more.