By comparing the expression of dozens of miRNAs in arterial plaque samples from patients who had or had not experienced a stroke, researchers have identified five miRNAs whose expression levels can help predict the risk of such symptoms.
Using a new biomarker-discovery workflow under development at BRIMS, researchers hope to find markers that may improve stroke patients' treatment options and shed light onto the biological mechanisms of the disease.
The "magnitude of net health benefit" from use of eight marketed tests analyzing 58 variants and 29 genes reviewed by the Evaluation of Genomic Applications in Practice and Prevention Working Group is "negligible," the expert panel wrote in a statement.
The deal will give cash-strapped Decode immediate access to an undisclosed sum in upfront payments, while Celera will gain access to gene markers that will expand its cardiovascular disease-focused genetic testing service.
Research conducted under the five-year CRADA could lead to the development of a new blood test that predicts patients at risk for heart disease and metabolic syndrome. The collaboration could also lead to the development of new targeted drugs.
DNAPrint, Laboratory Corporation of America, Duke University, Lab21, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Neurological Diseases and Stroke, and more …