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In search of blood biomarkers that could aid diagnosis and prognosis of patients with traumatic brain injury or who have a risk of stroke, Emory University researchers are planning two parallel biomarker studies using samples from participants enrolled in large multi-center clini

Thermo Fisher Scientific said this week that it has acquired protein biomarker firm Intrinsic Bioprobes, adding to its clinical proteomics portfolio.

By comparing the expression of dozens of miRNAs in arterial plaque samples from patients who had or had not experienced a stroke, researchers have identified five miRNAs whose expression levels can help predict the risk of such symptoms.

Using a new biomarker-discovery workflow under development at BRIMS, researchers hope to find markers that may improve stroke patients' treatment options and shed light onto the biological mechanisms of the disease.

Pronota will use its proprietary biomarker discovery platform MASStermind and verification platform MASSterclass on the project.

Pronota will use its MASStermind platform for the discovery stage of the deal, and its MASSterclass technology for the verification work.

The "magnitude of net health benefit" from use of eight marketed tests analyzing 58 variants and 29 genes reviewed by the Evaluation of Genomic Applications in Practice and Prevention Working Group is "negligible," the expert panel wrote in a statement.

Systems Biology in Action

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The Ottawa Institute of Systems Biology is still getting its momentum going, but it's already seen promising work in proteomics and spawned collaborations among its members.

The deal will give cash-strapped Decode immediate access to an undisclosed sum in upfront payments, while Celera will gain access to gene markers that will expand its cardiovascular disease-focused genetic testing service.

Research conducted under the five-year CRADA could lead to the development of a new blood test that predicts patients at risk for heart disease and metabolic syndrome. The collaboration could also lead to the development of new targeted drugs.

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Bloomberg reports that the DNA-for-cash deal reported in Kentucky might be a more widespread scam.

St. Jude Children's Research Hospital scientists have treated infants with X-linked severe combined immunodeficiency using gene therapy in an early phase study.

St. Louis Public Radio reports that some African Americans are turning to DNA ancestry testing to help guide genealogical searches.

In Nature this week: a genomic analysis of the snailfish Pseudoliparis swirei, ancient DNA analysis gives insight into the introduction of farming to England, and more.