stroke

By comparing the expression of dozens of miRNAs in arterial plaque samples from patients who had or had not experienced a stroke, researchers have identified five miRNAs whose expression levels can help predict the risk of such symptoms.

Using a new biomarker-discovery workflow under development at BRIMS, researchers hope to find markers that may improve stroke patients' treatment options and shed light onto the biological mechanisms of the disease.

Pronota will use its proprietary biomarker discovery platform MASStermind and verification platform MASSterclass on the project.

Pronota will use its MASStermind platform for the discovery stage of the deal, and its MASSterclass technology for the verification work.

The "magnitude of net health benefit" from use of eight marketed tests analyzing 58 variants and 29 genes reviewed by the Evaluation of Genomic Applications in Practice and Prevention Working Group is "negligible," the expert panel wrote in a statement.

Systems Biology in Action

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The Ottawa Institute of Systems Biology is still getting its momentum going, but it's already seen promising work in proteomics and spawned collaborations among its members.

The deal will give cash-strapped Decode immediate access to an undisclosed sum in upfront payments, while Celera will gain access to gene markers that will expand its cardiovascular disease-focused genetic testing service.

Research conducted under the five-year CRADA could lead to the development of a new blood test that predicts patients at risk for heart disease and metabolic syndrome. The collaboration could also lead to the development of new targeted drugs.

The collaboration with BG marks the first time the Framingham Heart Study has partnered with a commercial company on a CRADA project.

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DNAPrint, Laboratory Corporation of America, Duke University, Lab21, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Neurological Diseases and Stroke, and more …

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An analysis of UK Biobank data finds hemochromatosis to be more prevalent than thought, according to the BBC.

An analysis finds that female biomedical researchers receive fewer prizes than male ones, and when they do win prizes, they are less prestigious.

In Nature this week: improved genomic analysis using a graph genome reference, tumor mutational burden could predict clinical response to immune checkpoint inhibitors, and more.

Federal researchers tell the Los Angeles Times that the shutdown is causing missed research opportunities as they try to keep their experiments going.