stroke
Genomics PLC to Provide Polygenic Risk Scores for UK's Our Future Health Research Program
The company will work in partnership with Our Future Health to generate risk scores for up to 5 million people and to create methods for providing feedback to participants.
Stroke Risk Contributors, Treatment Targets Uncovered in Cross-Ancestry GWAS
Starting with a GWAS meta-analysis that included more than 110,000 stroke patients, researchers found new risk loci and developed polygenic scores for risk prediction.
As part of the program, point-of-care tests sold by Genedrive and Genomadix will be assessed, as well as laboratory-developed tests used within the UK National Health Service.
The firm said a test it has developed on the back of a large clinical trial detected cardioembolic stroke with 90 percent sensitivity and 70 percent specificity.
Genetic Study Explains Link Between Osteoporosis Drug, Cardiovascular Risk
The findings underscore the value of carrying out large-scale human genetic analyses as part of drug target identification and validation efforts.