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Staphylococcus

In PLOS this week: recessive mutation tied to early-onset dilated cardiomyopathy, epigenetic analysis of lung adenocarcinoma, and more.

A longitudinal household study suggests patients can acquire methicillin-resistant or sensitive Staphylococcus aureus from household members, pets, and surfaces.

Exome sequencing and other molecular strategies led to a heterogeneous variant in the DNMT3A gene that appears to impact host epigenetic and immune features.

In PNAS this week: blood plasma lipidome analysis of Ebola patients, genome organization of the malaria-causing parasite, and more.

The research highlighted particular challenges for gram-negative organisms among a population of higher-risk patients.

Signature Science will assess the validity of metagenomic and metatranscriptomic analyses to detect the transmission of viable pathogens in healthcare settings.

In PLOS this week: host genetic variants affecting Staphylococcus aureus bacteremia, differentially methylated regions in lung cancer, and more.

The amplicon sequencing method, called resistance mutation sequencing (RM-seq), may help in detecting resistance earlier than traditional techniques.

When researchers sequenced some 800 global Staphylococcus aureus isolates, they saw signs of previous jumps from humans to domestic animals and beyond.

The Vanderbilt researchers combined MALDI imaging-based proteomics, ICP-MS metal imaging, bioluminescent imaging, and MRI to study the development of staph infections.

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The US Food and Drug Administration is to announce stricter standards for emergency authorizations of SARS-CoV-2 vaccines, reports the Washington Post.

Bloomberg reports the budget of Operation Warp Speed is actually $18 billion, higher than the number typically cited.

The Associated Press reports Johnson & Johnson is starting a late-stage clinical trial of its candidate SARS-CoV-2 vaccine.

In Genome Research this week: genomic analysis reveals role of super-spreaders in SARS-CoV-2, epigenetic drivers of cancer, and more.