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squamous cell carcinoma

Esophageal Cancer Molecular Study Highlights Tumor Subtypes, Treatment Response Markers

Researchers found four esophageal squamous cell carcinoma molecular subtypes by generating genomic, transcriptomic, epigenetic, and proteomic profiles for more than 150 cases.

DermTech Using $144M Financing to Spur Marketing, Telemedicine Efforts For Molecular Melanoma Assay
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The firm expects to increase commercial coverage for its pigmented lesion assay for melanoma while widening its pipeline to diagnose other varieties of skin cancer.

BostonGene, Thomas Jefferson University Partner on Head, Neck Cancer Research

The partners will apply whole-exome and whole-transcriptome analysis to evaluate two existing drugs for squamous cell carcinoma treatment.

CRISPR Technique Targeting Tumor Cells Aims to Improve Chemo Efficacy
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Christiana Care researchers have identified a unique protospacer adjacent motif site that allows them to knock out the NRF2 gene in tumor cells while leaving normal cells alone.

New Iteration of AACR's Project GENIE Focuses on Real-World Outcomes to Enhance Precision Oncology
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The project is collaborating with nine biopharma companies to combine more real-world clinical data with genomic data.

Mar 12, 2020

Head and Neck Cancer Driver Mutations Affect NOTCH Pathway, CRISPR Screen Finds

Sep 11, 2019

German Team Classifies Lung Tumors With Methylation Profiles, Machine Learning Methods

Jul 16, 2019

Lung Cancer Study Points to Possible Blood Metabolomic Markers

May 30, 2019

PreCancer Atlas Attempts to Push Precision Medicine to Early-Stage Disease
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Apr 17, 2019

Non-Small Cell Lung Cancer Mutations, Tumor Microenvironment Profiled in China

Jan 23, 2019

Genomic Differences in Pre-Invasive Lung Cancer Lesions May Predict Outcome

Jan 10, 2019

Potential Prognostic Signature Described in HPV-Positive Squamous Cell Carcinomas

Aug 22, 2018

APOBEC-Linked Mutational Signatures Drive Skin Cancer in Recessive Dystrophic Epidermolysis Bullosa

Jun 25, 2018

Breast, Lung Cancer Outcomes Informed by Gene Expression of Individual Infiltrating T Cells

Jun 14, 2018

Breast, Lung Cancer Genetics Highlight Mutations Linked to Drug Response, Prognosis

Apr 3, 2018

TCGA Pan-Cancer Studies Describe New Tumor Features, Subtypes

Jan 29, 2018

Esophageal Cancer GWAS Leads to Low-Frequency Risk Variants

Aug 8, 2017

Transcriptomics Reveals Tissue-Agnostic Features in Adenocarcinomas, Squamous Cell Carcinomas

May 9, 2016

Lung Cancer Subtypes Have Different Recurrent Mutations, Study Finds

Sep 11, 2015

Launching Saliva Detection Test for Oral Cancer, PeriRx Sees Opportunity for Early-Stage Disease Dx
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Jun 17, 2014

NCI, Foundation Medicine, and Five Pharma Firms Kick off Lung-MAP Trial

May 30, 2013

Study Finds Lung Cancer Subtype Test from UNC, Startup GeneCentric to be Accurate, Reproducible
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Sep 10, 2012

TCGA Team Reports on Squamous Cell Lung Cancer Findings

Dec 23, 2009

Clarient Buys Applied Genomics to Pave Way to EGFR Testing Market for NSCLC
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The Scan

Study Points to Tuberculosis Protection by Gaucher Disease Mutation

A mutation linked to Gaucher disease in the Ashkenazi Jewish population appears to boost Mycobacterium tuberculosis resistance in a zebrafish model of the lysosomal storage condition, a new PNAS study finds.

SpliceVault Portal Provides Look at RNA Splicing Changes Linked to Genetic Variants

The portal, described in Nature Genetics, houses variant-related messenger RNA splicing insights drawn from RNA sequencing data in nearly 335,700 samples — a set known as the 300K-RNA resource.

Automated Sequencing Pipeline Appears to Allow Rapid SARS-CoV-2 Lineage Detection in Nevada Study

Researchers in the Journal of Molecular Diagnostics describe and assess a Clear Labs Dx automated workflow, sequencing, and bioinformatic analysis method for quickly identifying SARS-CoV-2 lineages.

UK Team Presents Genetic, Epigenetic Sequencing Method

Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers.