small cell lung cancer
Tempus, AstraZeneca Collaborate on Response Biomarker Discovery for Small Cell Lung Cancer
This clinical study, called Sculptor, is the first research to emerge from a strategic collaboration between the companies on oncology therapeutics.
Small Cell Lung Cancer Detection, Classification Achieved Using Cell-Free DNA Methylation
With a bisulfite-free sequencing method, researchers showed that they could identify and characterize SCLC based on circulating cell-free tumor DNA in blood samples.
Burning Rock Biotech, Impact Therapeutics Partner on CDx for PARP Inhibitor Senaparib
The NGS firm will work with Impact to develop companion diagnostics to select patients eligible for Impact's synthetic lethality drugs, beginning with senaparib.
Small Cell Lung Cancer Study Uncovers Disease-Associated Germline Mutations
The study, which showed that the disease may not only result from tobacco exposure as previously thought, could lay the groundwork for targeted therapies.
The transcription-based subtypes could differentiate which SCLC patients respond to treatments, such as immune checkpoint inhibitors and PARP inhibitors.