Using single-cell RNA sequencing and lineage tracing in a mouse model, researchers followed skin stem cell expression patterns in response to skin injury.
In Nature this week: Armillaria fungal genomes; risk variants linked to asthma, eczema, and hay fever; and more.
A genome-wide association meta-analysis involving hundreds of thousands of individuals led to 130 new and known risk variants linked to all three allergic conditions.
After identifying mutations in CARD11 in individuals with severe atopic dermatitis, investigators began untangling potential signaling consequences.
An autosomal dominant form of vibratory urticaria has been linked to a missense mutation in the ADGRE2 gene that appears to affect mast cell function and inflammation.
In Nature this week: DNA-free genome editing in plants, new risk loci for atopic dermatitis, and more.
Ten new atopic dermatitis risk loci turned up in a genome-wide association study meta-analysis involving hundreds of thousands of individuals.
Individuals who failed to clear a bacterial infection had variable skin microbiomes before exposure to the bug, but converged on similar skin microbiomes afterwards.
Nine members of the HMO Research Network "will use detailed clinical profiles to search for potential subjects to enroll into … serious adverse events research projects using their electronic medical record databases," iSAEC said in a statement.
Pharmacogenomics studies presented at the American Association for Cancer Research's annual meeting in Denver, Colo.
Bloomberg reports that the DNA-for-cash deal reported in Kentucky might be a more widespread scam.
St. Jude Children's Research Hospital scientists have treated infants with X-linked severe combined immunodeficiency using gene therapy in an early phase study.
St. Louis Public Radio reports that some African Americans are turning to DNA ancestry testing to help guide genealogical searches.
In Nature this week: a genomic analysis of the snailfish Pseudoliparis swirei, ancient DNA analysis gives insight into the introduction of farming to England, and more.