skin rash

After identifying mutations in CARD11 in individuals with severe atopic dermatitis, investigators began untangling potential signaling consequences.

An autosomal dominant form of vibratory urticaria has been linked to a missense mutation in the ADGRE2 gene that appears to affect mast cell function and inflammation.

This Week in Nature

In Nature this week: DNA-free genome editing in plants, new risk loci for atopic dermatitis, and more.

Ten new atopic dermatitis risk loci turned up in a genome-wide association study meta-analysis involving hundreds of thousands of individuals.

Individuals who failed to clear a bacterial infection had variable skin microbiomes before exposure to the bug, but converged on similar skin microbiomes afterwards.

Nine members of the HMO Research Network "will use detailed clinical profiles to search for potential subjects to enroll into … serious adverse events research projects using their electronic medical record databases," iSAEC said in a statement.

Pharmacogenomics studies presented at the American Association for Cancer Research's annual meeting in Denver, Colo.

The data, analyzed from biological samples donated by GlaxoSmithKline, is available on SAEC's website for free, and the group plans to publish the associations later this year. However, an SAEC official said "it would be preliminary to develop a meaningful diagnostic chip off this data."

Researchers find that a personalized medicine approach could help people who experience pain while taking statins, New Scientist reports.

US National Science Foundation is continuing its responsible research conduct training policy despite its flaws, ScienceInsider reports.

A CRISPR-themed meeting explored how the tool could and should be used, Wired reports.

In Science this week: database of proteins' effects on cancer, targeted error correction sequencing, and more.