sickle cell anemia

Nonprofit eMQT will use Shivom's decentralized blockchain platform to store and share genomic data of sickle-cell diseases in underserved regions.

With All of Us set to launch this weekend, the NIH director has been making the media rounds.

Data from almost 19,500 individuals did not show clear ties between a heterozygous mutation in the HBB hemoglobin beta gene and ischemic stroke risk.

National Human Genome Research Institute researchers report that the sickle cell mutation arose about 7,300 years ago.

Using haplotype profiling, phylogenetics, and other analyses, researchers retraced sickle allele emergence to a single event occurring roughly 7,300 years ago.

CRISPR Therapeutics is moving toward clinical trials for beta thalassemia and sickle cell disease treatments, according to Wired.

The wide-ranging discussion with witnesses from Stanford, Johns Hopkins, and Editas Medicine touched on recent advances in research and questions of safety.

Sickle Change

Stanford researchers use CRISPR to edit sickle cell mutations, possibly laying the groundwork for a clinical trial, Reuters reports.

This Week in Science

In Science this week: approach to uncover recent changes in allele frequencies, and more.

Utah's Dana Carroll, UC Berkeley's Jacob Corn, and their colleagues replaced the sickle cell disease mutation with the wild-type gene via HDR.

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Germany's Project DEAL has come to an agreement with the publisher Wiley over journal access and open-access publishing, ScienceInsider reports.

Researchers uncover additional loci associated with lifespan, which the Telegraph says could be folded into a genetic test.

A Canadian panel recommends public coverage of the gene therapy Kymriah if its cost comes down, the Globe and Mail reports.

In Nucleic Acids Research this week: new accurate quantification by sequencing approach, CNV breakpoints in Plasmodium falciparum, and more.