Researchers for the InPSYght project are sequencing 10,000 genomes and generating linked-read data for 500 to better understand schizophrenia and bipolar disorder.
Using genotyping and tissue-specific expression data from the Genotype-Tissue Expression project, researchers characterized Neanderthal allele-specific expression.
The international team of researchers also examined the genetic ties between personality traits and psychiatric disorders.
Using CNV profiles for more than 40,000 individuals with or without schizophrenia, researchers got a refined look at gains and losses linked to the condition.
In Genome Biology this week: single-cell transcriptomic study of embryonic stem cell differentiation, epigenome-wide association study of schizophrenia, and more.
Blood tests looking for biomarker changes could catch mental illnesses earlier, Newsweek reports.
Through their combined genetic and epigenetic study of schizophrenia, the researchers have generated a list of genes affected by risk factors for the disease.
They found that hippocampal long-term potentiation triggered changes in protein signaling, including to a number of proteins linked to these disorders.
Data from 43 genome-wide association studies have led researchers to individual variants and genetic factors that influence multiple phenotypes and conditions.
A University of Pittsburgh research team used a novel computational approach to uncover the protein interactions, which may be potential treatment targets.
An opinion piece in the New York Times urges lawmakers to keep genetic protections in place.
Research funding in Canada is to remain mostly the same, ScienceInsider reports.
In Science this week: random DNA replication errors play role in cancer, and more.
The Bill and Melinda Gates Foundation embarks on an open-access publishing path.