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schizophrenia

An epigenome-wide association study of major psychosis uncovered hypomethylation at an enhancer that targets a gene involved in dopamine synthesis.

To understand the evolution of brain conditions and other traits, investigators plan to sequence human and pathogen DNA in thousands of samples from Europe.

Researchers focused in on strong candidate genes in schizophrenia with brain anatomy, brain activity, and behavioral screens on a large set of zebrafish mutants.

This Week in Nature

In Nature this week: GWAS of cigarette smoking behaviors, set of gene expression predictors for schizophrenia, and more.

With available brain data, researchers came up with expression prediction models for finding new schizophrenia-related genes in a larger case-control set.

Researchers used a genome-wide association study to identify seven loci associated with ASD and other conditions, along with five loci linked to ASD alone.

Researchers prioritized schizophrenia risk SNPs from genome-wide association studies and used functional genomics to find transcription factor-disrupting risk SNPs.

This Week in Science

In Science this week: discussion of combining immunotherapies with targeted treatments, and more.

Two independent teams described potential roles for gut microbes, and the compounds they produce, in schizophrenia, depression, and mental quality of life.

Polygenic risk scores for depression, bipolar disorder, and schizophrenia are associated with depression in a general population cohort.

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The chief executive of the National Health Service in England is to call for tumor-agnostic drugs to be "fast-tracked," according to the Times.

Researchers in Australia are sequencing the Wollemi pine tree to try to protect it from extinction, Australia's ABC News reports.

Computerworld ranks Illumina as one of the top midsize organizations to work at in IT.

In Genome Research this week: links between biological aging and mutations affecting epigenetic regulators; long-read sequencing-based strategy to map chromatin accessibility; and more.