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schizophrenia

In PLOS this week: phenome-wide association study of psychiatric disorder polygenic risk scores, CNV patterns in rhesus macaques, and more.

The study also found that certain genes may influence multiple complex traits, while others only affect one phenotype, making them worthwhile therapeutic targets.

In Nature this week: missense variant linked to decreased height among Peruvians, genetic basis of sex-biased vulnerability to certain disorders, and more.

The analysis of a hippocampus cell layer uncovered genetic loci associated with schizophrenia risk, including two that may represent drug targets.

Investigators tracked down a methylation signature in blood that corresponded with features found in postmortem brain samples from schizophrenia cases.

In Science this week: genetic mutation linked to schizophrenia among South African Xhosas, engineering the bee microbiome to address parasite and virus, and more.

An analysis of cases and controls from South Africa's Xhosa population pointed to private, damaging mutations in genes expressed in the brain.

While de novo mutations appeared to make relatively modest contributions to schizophrenia risk, they recurrently affected evolutionarily conserved genes.

Some of these shared loci were associated with higher BMI, but some were linked to lower BMI, particularly those also linked to schizophrenia.

A genome-wide association study involving some 200,000 veterans unearthed five anxiety risk loci in European Americans and another risk locus in African Americans.

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Novavax has begun a phase III trial of its SARS-CoV-2 vaccine, according to the New York Times.

Vox reports that the Trump Administration may limit student visas for individuals from some countries to two years.

The governor of New York says the state will conduct its own review of any SARS-CoV-2 vaccine, NPR reports.

This week in Science: Neanderthal Y chromosomes replaced by Homo sapiens Y chromosomes, and more.