schizophrenia
Low-Coverage Sequencing Effectively IDs Novel Variants in Underrepresented Populations
The researchers found that sequencing at a depth of 4x or higher captured
Ultra-Rare Genetic Variants in Protocadherin Gene Linked to Schizophrenia
By focusing their genomic analysis on an Ashkenazi Jewish population, researchers uncovered ultra-rare variants associated with schizophrenia.
Case-Case GWAS Approach Identifies Loci That Differ in Frequency Across Psychiatric Disorders
The approach provides new insights into genetic differences between various disorders in order to improve their diagnosis and treatment.
Spatial Transcriptomics Study Refines View Across Layers of Human Brain Region
Spatial expression features in six layers of the human dorsolateral prefrontal cortex provided a look at laminar markers and discovered ties to neuropsychiatric disease genes.
Psychiatric Disorder Risk Affected by Dysregulation of RNA-Binding Proteins
Using a deep learning approach to study mutations in target sites of RNA-binding proteins, researchers identified DDHD2 as a candidate schizophrenia risk gene.