schizophrenia Rare Single-Gene Variants Confer High Risk for Mental Health Conditions, Geisinger Study Shows Premium Researchers suggest physicians should more routinely order genetic testing for patients with mental health disorders, a group that has historically been undertested. Study Links Maternal Mental Illness-Related Variants to Perinatal Risk Factors For Offspring Researchers identified relationships between pregnancy-related maternal traits and behaviors and polygenic risk scores for half a dozen mental health conditions. Cross-Trait Meta-Analysis Explores Potential Pleiotropy Across Psychiatric Conditions Researchers considered genetic overlap between pairs of psychiatric conditions and across 12 psychiatric disorders, highlighting evolutionarily conserved parts of the genome. Schizophrenia Neuron Single-Nucleus Sequencing Study Finds Impairment in Upper Cortex Layers Researchers found that different types of neurons undergo changes in individuals with schizophrenia, as compared to unaffected individuals. Neuropsychiatric Disease Clues Drawn From Enhancer Expression Analysis Researchers investigated the variation in enhancer expression within a population, using the clues to better understand the risk of neuropsychiatric conditions such as schizophrenia. Sep 14, 2022 Polygenic Risk Scores for Neuropsychiatric Conditions in Civilians Are Generalizable to Veterans Aug 17, 2022 Schizophrenia Study Implicates Ultrarare Variants in Cognitive Features Jun 23, 2022 NYGC Psychiatric Disease Database Project Aims to Kickstart Precision Medicine for Mental Illness Premium Apr 6, 2022 Schizophrenia, Bipolar Disorder Risk Traced to Common, Rare Variants in New Genetic Studies Jan 21, 2022 New Approach Identifies Candidate Causal Variants for Neuropsychiatric, Neurodevelopmental Conditions Oct 27, 2021 Polygenic Risk Scores Edge Toward Clinic, Though Disease Prediction Utility Questions Linger Premium Oct 22, 2021 SUPER Psychosis Study Presented at ASHG Digs Into Relationships of Rare Variants, Phenotypes Sep 7, 2021 Polygenic Risk Score Addition Does Not Improve Models Predicting Schizophrenia Prognosis Mar 26, 2021 Low-Coverage Sequencing Effectively IDs Novel Variants in Underrepresented Populations Mar 22, 2021 Ultra-Rare Genetic Variants in Protocadherin Gene Linked to Schizophrenia Mar 8, 2021 Case-Case GWAS Approach Identifies Loci That Differ in Frequency Across Psychiatric Disorders Feb 8, 2021 Spatial Transcriptomics Study Refines View Across Layers of Human Brain Region Jan 19, 2021 Psychiatric Disorder Risk Affected by Dysregulation of RNA-Binding Proteins May 14, 2020 Brain Proteins May Mediate Effects of Genetic Variants on Some Neurological Phenotypes Mar 16, 2020 Gene Expression Study of Brain Cell Layer Finds New Schizophrenia Risk Loci Feb 12, 2020 Schizophrenia Associated With Blood DNA Methylation Signature Jan 30, 2020 Schizophrenia Exome Sequencing Study in South African Population Reveals Rare Mutations, Pathways Jan 14, 2020 Schizophrenia Exome Studies Delineate Role of De Novo Mutations Jan 8, 2020 Psychiatric Disorders, Body Mass Index Share Genetic Loci, Study Finds Jan 7, 2020 Anxiety GWAS On Million Veteran Program Data Uncovers New Loci Load More Breaking News Cancer Prognoses Informed by Module-Based Approach, Study Finds People in the News at Illumina, Centogene, BioSkryb New Products Posted to GenomeWeb: Bio-Rad, BD, Analytik Jena, BioMérieux Genetic Technologies to Raise A$5M in Direct Stock Offering In Brief This Week: SD Biosensors, Meridian, Oncocyte, Opko Health, GeneDx, More The Scan Study Reveals New Details About Genetics of Major Cause of Female Infertility Researchers in Nature Medicine conducted a whole-exome sequencing study of mote than a thousand patients with premature ovarian insufficiency. Circulating Tumor DNA Shows Potential as Biomarker in Rare Childhood Cancer A study in the Journal of Clinical Oncology has found that circulating tumor DNA levels in rhabdomyosarcoma may serve as a biomarker for prognosis. Study Recommends Cancer Screening for Dogs Beginning Age Seven, Depending on Breed PetDx researchers report in PLOS One that annual cancer screening for dogs should begin by age seven. White-Tailed Deer Harbor SARS-CoV-2 Variants No Longer Infecting Humans, Study Finds A new study in PNAS has found that white-tailed deer could act as a reservoir of SARS-CoV-2 variants no longer found among humans.