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A five-gene signature was linked to both event-free survival and overall survival in individuals with a type of rhabdomyosarcoma missing a prognostically informative gene fusion.

The group is currently comparing a lab-developed nCounter assay to "gold-standard" RT-PCR assays to retrospectively analyze sarcoma patient samples.

MGH runs the clinical fusion assay for all lung cancer patients and the Snapshot NGS test on all patients with solid tumors. It is planning to expand the assays and is also developing a fusion panel for hematological malignancies.

NEW YORK (GenomeWeb News) – The Sarcoma Alliance for Research through Collaboration, or SARC, today announced it has received a five-year, $11.5 million grant from the National Cancer Institute to conduct translational research into sarcoma, a relatively rare cancer than can affect bones and soft

The research team analyzed a combination of DNA sequence, copy number, and mRNA expression to identify several genes associated with soft-tissue sarcoma subtypes.

Recent Research Papers of Note

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Included is a paper on the use of a mass spectrometry-based strategy for the absolute quantification of protein complex components, one using SISCAPA technology, and one showing that top-down proteomics can be done using CID on a q-TOF instrument.

A Whole New System

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Now in its ninth year, the experiment that was the Institute for Systems Biology has become an established research organization known for its focus on translational science.

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Researchers tie a variant in ADAMTS3 to breathing difficulties in dissimilar dog breeds, according to Discover's D-brief blog.

The Japan Times reports that researchers sequenced the genome of a woman who lived during the Jomon period.

Parents of children with rare genetic disease have to contend with shifts in the interpretation of genetic variants, the Wall Street Journal reports.

In Science this week: single-nucleus RNA sequencing of brain tissue from individuals with autism, and more.