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A five-gene signature was linked to both event-free survival and overall survival in individuals with a type of rhabdomyosarcoma missing a prognostically informative gene fusion.

The group is currently comparing a lab-developed nCounter assay to "gold-standard" RT-PCR assays to retrospectively analyze sarcoma patient samples.

MGH runs the clinical fusion assay for all lung cancer patients and the Snapshot NGS test on all patients with solid tumors. It is planning to expand the assays and is also developing a fusion panel for hematological malignancies.

NEW YORK (GenomeWeb News) – The Sarcoma Alliance for Research through Collaboration, or SARC, today announced it has received a five-year, $11.5 million grant from the National Cancer Institute to conduct translational research into sarcoma, a relatively rare cancer than can affect bones and soft

The research team analyzed a combination of DNA sequence, copy number, and mRNA expression to identify several genes associated with soft-tissue sarcoma subtypes.

Included is a paper on the use of a mass spectrometry-based strategy for the absolute quantification of protein complex components, one using SISCAPA technology, and one showing that top-down proteomics can be done using CID on a q-TOF instrument.

A Whole New System

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Now in its ninth year, the experiment that was the Institute for Systems Biology has become an established research organization known for its focus on translational science.

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A new analysis finds that nearly half the late-stage clinical trials sponsored by a US National Cancer Institute program influence patient care.

Technology Review reports that sickle cell patients are optimistic about gene editing to treat their disease, but are worried about how available it will be.

The owner of the GEDmatch website tells CBS12 he is considering charging law enforcement a fee to use the site.

In Nature this week: babies born by caesarean section are more likely to have altered gut microbiota profiles, and more.