sarcoma
Personalized Residual Disease Assays Show Promise to Overcome Liquid Biopsy Challenges in Sarcomas
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New data presented at the ASCO annual meeting this week showed that tumor-informed assays could detect emerging recurrence ahead of imaging.
BostonGene, Little Warrior Foundation Partner to Develop Sarcoma-Specific Liquid Biopsy
Liquid biopsy tests will be designed to detect molecular alterations and fusions specific to sarcoma using cell-free DNA and RNA.
The liquid biopsy assay uses low-pass whole-genome sequencing to screen for copy number alterations in blood, cerebral spinal fluid, and aqueous humor samples.
Ewing Sarcoma Risk Locus Analysis Sheds Light on Cancer's Formation
Analyzing a chromosome 6 risk locus by long-read sequencing, researchers saw a combination of germline and somatic alterations interacting in the development of Ewing sarcoma.
Sarcoma Susceptibility Traced to Telomere Function, Mitotic Pathways
A search for rare sarcoma-related germline variants led to centromere and shelterin genes involved in mitotic function and telomere regulation, respectively.