sarcoma Cancer Risk Variants Found in Significant Subset of Sarcoma Patient Germlines A retrospective analysis of multi-gene panel tests for more than 300 adult sarcoma patients unearthed pathogenic or likely pathogenic variants in cancer genes in 16 percent of cases. Blood Testing Distinguishes Benign Tumors From Precancerous Condition Researchers used ultra-low-pass whole genome sequencing and cell-free DNA fragment size selection to detect pre-cancer in neurofibromatosis type 1 patients. Tool Detects Pediatric Bone Tumors From Liquid Biopsies Based on Epigenetic Profiles Epigenetic signatures of Ewing sarcoma affect cell-free DNA fragmentation patterns and can be used to detect cancer. Nonprofit Count Me In to Return Genomic Results to Patients With Rare Cancers Premium With a new $16 million NCI grant, Count Me In is working with the Broad and Dana-Farber to engage osteosarcoma and leiomyosarcoma patients in their own care and in research. Secondary Tumor Risk in Pediatric Cancer Survivors Linked to Germline Variants, Treatment Type An analysis of pediatric cancer survivors suggests subsequent neoplasm risk can increase after certain genotoxic treatments in those with DNA repair gene changes. Apr 16, 2020 Human Tumor Atlas Network Team Shares Strategy for Tracking Tumor Transitions Jan 22, 2020 B Cell Gene Expression Profiling May Enable Cancer Immunotherapy CDx Test Premium Jan 15, 2020 Presence of B Cells in Tumors Associated With Favorable Immunotherapy Outcomes Mar 31, 2019 CAR T Cell Therapies Targeting HER2, Mesothelin Show Activity in Solid Tumors Premium Oct 18, 2018 Broad Institute Launches Patient-Partnered Cancer Research Non-Profit Organization Aug 30, 2018 Subset of Ewing Sarcomas Arise from Early, Complex Genome Rearrangements Aug 23, 2018 Multi-Omic Analysis of Rhabdomyosarcoma Points to Drug Targets in Deregulated Pathways Aug 23, 2018 Researchers Validate ArcherDx Targeted Sequencing Approach for Sarcoma Gene Fusions Premium Jun 18, 2018 Recurrent Rearrangements Identified in Rare Infant Soft Tissue Tumors Jun 4, 2018 MSI Tumor Analysis Implicates Lynch Syndrome in Several New Cancer Types Apr 19, 2018 AACR Symposium Features Genomic, Proteomic Searches for Immunotherapy Improvements Mar 20, 2018 Cofactor Genomics, NCI Partner to Validate RNA-Based Immune Profiling Assay Feb 16, 2018 Cofactor Pushes RNA-Based Dx Goals With New Immuno-Oncology Assay Premium Nov 17, 2017 NanoString-Based Pan-Sarcoma Fusion Gene Assay Shows Promise as First-Line Dx Premium Jun 3, 2017 French Genome Profiling Trial Points to Frequent Actionable Mutations in Advanced Cancer May 8, 2017 Oxford Gene Technology Bets on Design, Flexibility to Woo Clinical Labs With New NGS Cancer Panel Premium Jan 31, 2017 Ewing Sarcomas Contain Spectrum of DNA Methylation Changes Jan 30, 2017 Columbia U, Life Raft Use Pathway Approach to Find New Therapies for Resistant GI Tumors Premium Aug 5, 2016 Sarcoma Patient Targeted Sequencing IDs Germline Mutations in Known Cancer Genes Jun 22, 2016 NIH Panel Approves CRISPR-Edited T Cell Safety Trial, First In-Human Use Premium Load More Breaking News 23andMe Fiscal Q4 Revenues Increase 14 Percent Local Coverage Determinations Roundup: Castle Bio, SkylineDx Ancient Genome Sequence Provides Look at Ancestry for Individual Who Perished at Pompeii Allogeneic Stem Cell Transplant Outcomes Improve With Diverse Gut Microbes, Immune Cells CorePath Laboratories, Cizzle Biotechnology Partner on Lung Cancer Blood Test Becton Dickinson Gets CE-IVD Mark for High-Throughput COVID/Flu PCR Test The Scan Billion-Dollar Diversity Initiative The Howard Hughes Medical Institute is now accepting applications for its new $1.5 billion initiative to boost the diversity of the scientific workforce. Biotech Co-Founder Arrested A co-founder of a Los Angeles-based biotech company has been arrested in connection with a murder-for-hire scheme, according to Endpoint News. Return of the Tasmanian Tiger The Washington Post reports that a team in Australia is working to bring the thylacine back from extinction. Nature Papers on Genome of Individual From Pompeii, CircRNA Study Best Practices, More In Nature this week: first sequenced genome of a person from Pompeii, best practice guidelines for circRNA studies, and more.