sarcoma Tool Detects Pediatric Bone Tumors From Liquid Biopsies Based on Epigenetic Profiles Epigenetic signatures of Ewing sarcoma affect cell-free DNA fragmentation patterns and can be used to detect cancer. Nonprofit Count Me In to Return Genomic Results to Patients With Rare Cancers Premium With a new $16 million NCI grant, Count Me In is working with the Broad and Dana-Farber to engage osteosarcoma and leiomyosarcoma patients in their own care and in research. Secondary Tumor Risk in Pediatric Cancer Survivors Linked to Germline Variants, Treatment Type An analysis of pediatric cancer survivors suggests subsequent neoplasm risk can increase after certain genotoxic treatments in those with DNA repair gene changes. Human Tumor Atlas Network Team Shares Strategy for Tracking Tumor Transitions A new paper outlines an upcoming effort to trace tumor development and trajectory in time and space using single-cell genetics and other genomic methods. B Cell Gene Expression Profiling May Enable Cancer Immunotherapy CDx Test Premium Researchers have identified immune cell gene expression signatures that could one day be developed into tests to predict response to treatment. Jan 15, 2020 Presence of B Cells in Tumors Associated With Favorable Immunotherapy Outcomes Mar 31, 2019 CAR T Cell Therapies Targeting HER2, Mesothelin Show Activity in Solid Tumors Premium Oct 18, 2018 Broad Institute Launches Patient-Partnered Cancer Research Non-Profit Organization Aug 30, 2018 Subset of Ewing Sarcomas Arise from Early, Complex Genome Rearrangements Aug 23, 2018 Multi-Omic Analysis of Rhabdomyosarcoma Points to Drug Targets in Deregulated Pathways Aug 23, 2018 Researchers Validate ArcherDx Targeted Sequencing Approach for Sarcoma Gene Fusions Premium Jun 18, 2018 Recurrent Rearrangements Identified in Rare Infant Soft Tissue Tumors Jun 4, 2018 MSI Tumor Analysis Implicates Lynch Syndrome in Several New Cancer Types Apr 19, 2018 AACR Symposium Features Genomic, Proteomic Searches for Immunotherapy Improvements Mar 20, 2018 Cofactor Genomics, NCI Partner to Validate RNA-Based Immune Profiling Assay Feb 16, 2018 Cofactor Pushes RNA-Based Dx Goals With New Immuno-Oncology Assay Premium Nov 17, 2017 NanoString-Based Pan-Sarcoma Fusion Gene Assay Shows Promise as First-Line Dx Premium Jun 3, 2017 French Genome Profiling Trial Points to Frequent Actionable Mutations in Advanced Cancer May 8, 2017 Oxford Gene Technology Bets on Design, Flexibility to Woo Clinical Labs With New NGS Cancer Panel Premium Jan 31, 2017 Ewing Sarcomas Contain Spectrum of DNA Methylation Changes Jan 30, 2017 Columbia U, Life Raft Use Pathway Approach to Find New Therapies for Resistant GI Tumors Premium Aug 5, 2016 Sarcoma Patient Targeted Sequencing IDs Germline Mutations in Known Cancer Genes Jun 22, 2016 NIH Panel Approves CRISPR-Edited T Cell Safety Trial, First In-Human Use Premium Nov 2, 2015 Team Finds Recurrent Fusion in Aggressive Angiosarcomas Oct 15, 2015 Findings Support Prognostic Potential for Gene Signature in Some Forms of Rhabdomyosarcoma Load More Breaking News OraSure Technologies Q2 Revenues Nearly Double 908 Devices Q2 Revenues Drop 25 Percent but Beat Wall Street Estimate Thermo Fisher Scientific, Access Bio, LumiraDx Get FDA Emergency Use Authorizations for SARS-CoV-2 Tests Pacific Biosciences Q2 Revenues Grow 79 Percent Invitae More Than Doubles Q2 Revenues CRISPR Researchers Engineer Guide RNAs to Enhance Cas13 Gene Knockdown The Scan Push Toward Approval The Wall Street Journal reports the US Food and Drug Administration is under pressure to grant full approval to SARS-CoV-2 vaccines. Deer Exposure About 40 percent of deer in a handful of US states carry antibodies to SARS-CoV-2, according to Nature News. Millions But Not Enough NPR reports the US is set to send 110 million SARS-CoV-2 vaccine doses abroad, but that billions are needed. PNAS Papers on CRISPR-Edited Cancer Models, Multiple Sclerosis Neuroinflammation, Parasitic Wasps In PNAS this week: gene-editing approach for developing cancer models, role of extracellular proteins in multiple sclerosis, and more.