sarcoma Blood Testing Distinguishes Benign Tumors From Precancerous Condition Researchers used ultra-low-pass whole genome sequencing and cell-free DNA fragment size selection to detect pre-cancer in neurofibromatosis type 1 patients. Tool Detects Pediatric Bone Tumors From Liquid Biopsies Based on Epigenetic Profiles Epigenetic signatures of Ewing sarcoma affect cell-free DNA fragmentation patterns and can be used to detect cancer. Nonprofit Count Me In to Return Genomic Results to Patients With Rare Cancers Premium With a new $16 million NCI grant, Count Me In is working with the Broad and Dana-Farber to engage osteosarcoma and leiomyosarcoma patients in their own care and in research. Secondary Tumor Risk in Pediatric Cancer Survivors Linked to Germline Variants, Treatment Type An analysis of pediatric cancer survivors suggests subsequent neoplasm risk can increase after certain genotoxic treatments in those with DNA repair gene changes. Human Tumor Atlas Network Team Shares Strategy for Tracking Tumor Transitions A new paper outlines an upcoming effort to trace tumor development and trajectory in time and space using single-cell genetics and other genomic methods. Jan 22, 2020 B Cell Gene Expression Profiling May Enable Cancer Immunotherapy CDx Test Premium Jan 15, 2020 Presence of B Cells in Tumors Associated With Favorable Immunotherapy Outcomes Mar 31, 2019 CAR T Cell Therapies Targeting HER2, Mesothelin Show Activity in Solid Tumors Premium Oct 18, 2018 Broad Institute Launches Patient-Partnered Cancer Research Non-Profit Organization Aug 30, 2018 Subset of Ewing Sarcomas Arise from Early, Complex Genome Rearrangements Aug 23, 2018 Multi-Omic Analysis of Rhabdomyosarcoma Points to Drug Targets in Deregulated Pathways Aug 23, 2018 Researchers Validate ArcherDx Targeted Sequencing Approach for Sarcoma Gene Fusions Premium Jun 18, 2018 Recurrent Rearrangements Identified in Rare Infant Soft Tissue Tumors Jun 4, 2018 MSI Tumor Analysis Implicates Lynch Syndrome in Several New Cancer Types Apr 19, 2018 AACR Symposium Features Genomic, Proteomic Searches for Immunotherapy Improvements Mar 20, 2018 Cofactor Genomics, NCI Partner to Validate RNA-Based Immune Profiling Assay Feb 16, 2018 Cofactor Pushes RNA-Based Dx Goals With New Immuno-Oncology Assay Premium Nov 17, 2017 NanoString-Based Pan-Sarcoma Fusion Gene Assay Shows Promise as First-Line Dx Premium Jun 3, 2017 French Genome Profiling Trial Points to Frequent Actionable Mutations in Advanced Cancer May 8, 2017 Oxford Gene Technology Bets on Design, Flexibility to Woo Clinical Labs With New NGS Cancer Panel Premium Jan 31, 2017 Ewing Sarcomas Contain Spectrum of DNA Methylation Changes Jan 30, 2017 Columbia U, Life Raft Use Pathway Approach to Find New Therapies for Resistant GI Tumors Premium Aug 5, 2016 Sarcoma Patient Targeted Sequencing IDs Germline Mutations in Known Cancer Genes Jun 22, 2016 NIH Panel Approves CRISPR-Edited T Cell Safety Trial, First In-Human Use Premium Nov 2, 2015 Team Finds Recurrent Fusion in Aggressive Angiosarcomas Load More Breaking News GenomeWeb Index Falls 6 Percent in November as Emergence of Omicron Spooks Markets Sequencing-Based MRD Detection in Bone Marrow May Predict ALL Relapse After CAR T-Cell Therapy Metabolomic Study Links 13 Metabolites to Coronary Heart Disease Risk Among African Americans Illumina Wins $8M Jury Verdict in BGI Patent Infringement Suit, Loses Patent Caris Life Sciences Facing FTC Lawsuit After Resisting Subpoena in Illumina, Grail Antitrust Case Biodesix, Spesana Partner to Improve Workflows for Lung Cancer Molecular Diagnostic Tests The Scan Panel Votes for COVID-19 Pill A US Food and Drug Administration panel has voted to support the emergency use authorization of an antiviral pill for COVID-19 from Merck and Ridgeback Biotherapeutics, CNN says. But Not Harm New Scientist reports that UK bioethicists say that though gene editing may improve food production, it should not harm livestock welfare. Effectiveness Drop Anticipated Moderna's Stéphane Bancel predicts that that current SARS-CoV-2 vaccines may be less effective against the Omicron variant, the Financial Times reports. Cell Studies of Human Chromatin Accessibility, SARS-CoV-2 Variants, Cell Signaling Networks In Cell this week: chromatin accessibility maps of adult human tissues, modeling to track SARS-CoV-2 variants of concern, and more.