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Personalized Residual Disease Assays Show Promise to Overcome Liquid Biopsy Challenges in Sarcomas
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New data presented at the ASCO annual meeting this week showed that tumor-informed assays could detect emerging recurrence ahead of imaging.

BostonGene, Little Warrior Foundation Partner to Develop Sarcoma-Specific Liquid Biopsy

Liquid biopsy tests will be designed to detect molecular alterations and fusions specific to sarcoma using cell-free DNA and RNA.

CHLA Low-Pass WGS Liquid Biopsy Assay Could Aid Pediatric Cancer Diagnosis, Prognosis
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The liquid biopsy assay uses low-pass whole-genome sequencing to screen for copy number alterations in blood, cerebral spinal fluid, and aqueous humor samples.

Ewing Sarcoma Risk Locus Analysis Sheds Light on Cancer's Formation

Analyzing a chromosome 6 risk locus by long-read sequencing, researchers saw a combination of germline and somatic alterations interacting in the development of Ewing sarcoma.

Sarcoma Susceptibility Traced to Telomere Function, Mitotic Pathways

A search for rare sarcoma-related germline variants led to centromere and shelterin genes involved in mitotic function and telomere regulation, respectively.

Jan 18, 2023

Researchers Validate Rapid Molecular Kaposi's Sarcoma Assay in Uganda
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Jun 29, 2022

Sarcoma Patients Should Receive Genomic Profiling More Often, Research Suggests
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Mar 25, 2022

Cancer Risk Variants Found in Significant Subset of Sarcoma Patient Germlines

Aug 31, 2021

Blood Testing Distinguishes Benign Tumors From Precancerous Condition

May 28, 2021

Tool Detects Pediatric Bone Tumors From Liquid Biopsies Based on Epigenetic Profiles

Mar 3, 2021

Nonprofit Count Me In to Return Genomic Results to Patients With Rare Cancers
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Jun 5, 2020

Secondary Tumor Risk in Pediatric Cancer Survivors Linked to Germline Variants, Treatment Type

Apr 16, 2020

Human Tumor Atlas Network Team Shares Strategy for Tracking Tumor Transitions

Jan 22, 2020

B Cell Gene Expression Profiling May Enable Cancer Immunotherapy CDx Test
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Jan 15, 2020

Presence of B Cells in Tumors Associated With Favorable Immunotherapy Outcomes

Mar 31, 2019

CAR T Cell Therapies Targeting HER2, Mesothelin Show Activity in Solid Tumors
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Oct 18, 2018

Broad Institute Launches Patient-Partnered Cancer Research Non-Profit Organization

Aug 30, 2018

Subset of Ewing Sarcomas Arise from Early, Complex Genome Rearrangements

Aug 23, 2018

Multi-Omic Analysis of Rhabdomyosarcoma Points to Drug Targets in Deregulated Pathways

Aug 23, 2018

Researchers Validate ArcherDx Targeted Sequencing Approach for Sarcoma Gene Fusions
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Jun 18, 2018

Recurrent Rearrangements Identified in Rare Infant Soft Tissue Tumors

Jun 4, 2018

MSI Tumor Analysis Implicates Lynch Syndrome in Several New Cancer Types

Apr 19, 2018

AACR Symposium Features Genomic, Proteomic Searches for Immunotherapy Improvements

Mar 20, 2018

Cofactor Genomics, NCI Partner to Validate RNA-Based Immune Profiling Assay

Feb 16, 2018

Cofactor Pushes RNA-Based Dx Goals With New Immuno-Oncology Assay
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The Scan

Hormone-Based Gene Therapy to Sterilize Domestic Cat

A new paper in Nature Communication suggests that gene therapy could be a safer alternative to spaying domestic cats.

Active Lifestyle Linked to Type 2 Diabetes Prevention in People at High Genetic Risk

A study in the British Journal of Sports Medicine shows that an active lifestyle goes a long way in type 2 diabetes prevention.

Beneficial, Harmful Effects of Introgression Between Wild and Domesticated European Grapes

A paper in PNAS shows that European wild grapevines were an important resource for improving the flavor of cultivated wine grapes.

Genetic Ancestry of South America's Indigenous Mapuche Traced

Researchers in Current Biology analyzed genome-wide data from more than five dozen Mapuche individuals to better understand their genetic history.