Sequencing of typhoid fever outbreak samples in Pakistan indicates extensive drug resistance arose when a local multidrug resistance strain acquired a new plasmid.
In PLOS this week: metabolite profiles of typhoid fever, shifts in cell-free DNA levels following exercise, and more.
In Nature this week: Salmonella enterica uncovered in 16th century Mexico cemeteries, reconstruction of Hans Jonatan's genome, and more.
Max Planck researchers screened metagenomic data from samples from an outbreak-era Mexican cemetery to find Salmonella enterica DNA.
In PNAS this week: host contributors to typhoid fever risk, effects of obesity-related variants near TMEM18, and more.
In PLOS this week: genomic analysis of common liver fluke, genomic changes in Salmonella Typhi after vaccine introduction, and more.
Researchers from the CDC and Georgia Tech tested the efficacy of using whole-genome shotgun sequencing to diagnose food-borne pathogens in outbreaks.
Different clades of Salmonella enterica serovar Enteritidis are behind the self-limiting and invasive diseases the bacterium causes in different parts of the world.
The researchers sequenced bacteria samples sourced from all over the world to reconstruct a phylogenetic tree and learn how it evolved to have multidrug resistance.
In PLOS this week: recombination density-based method for calibrating human mutation rates, pathogen-typing approach using solid-state nanopores, and more.
Robert Redfield is floated as the next director of the US Centers for Disease Control and Prevention, the Washington Post reports.
The New York Times writes that the National Institutes of Health's All of Us Research Program is "ambitious" and that some are concerned it might be overly so.
Representative Lamar Smith's criticism of the National Science Foundation has "changed the nature of the conversation," according to ScienceInsider.
In PLOS this week: non-coding RNA function in yeast, transcriptomic profiles of malaria parasites, and more.