The studies looked at applications including predicting disease progression, guiding drug tapering, and identifying patients at risk of related conditions.
Results from the Rheumatoid Arthritis Responder Dream Challenge did not support the use of common SNP data to improve treatment response prediction models.
Firalis is developing an assay based on HTG's EdgeSeq platform to identify rheumatoid arthritis patients likely to respond to anti-TNF-alpha therapies.
IQuity's current tests analyze gene expression patterns detected in mRNA, but the firm is also exploring the diagnostic potential of long non-coding RNAs.
The approach can increase CpG coverage about 18-fold by inferring from existing data to predict methylation of sites outside those covered on the arrays themselves.
In PLOS this week: researchers trace inherited cancer syndrome to a German couple born in the 1700s, loci involved in exceptional longevity, and more.
The company hopes to identify a subset of predictive markers from a current panel of 100 proteins it identified as possibly useful through previous RA studies.
The company presented new data at a meeting last week showing that Vectra DA predicted whether patients would do better on one or the other of two possible second-line therapies.
If it is able to implement its strategic goals, Myriad projected, it could have $1.5 billion in annual revenues by fiscal year 2020.
The oral and gut microbiomes of people with rheumatoid arthritis suffer from dysbiosis, which is partially normalized after treatment, according to metagenomic studies.
In Science this week: genetic analysis of pollutant-tolerant fish, and more.
Researchers have found a rare carbapenem resistance gene on a US pig farm, NBC News reports.
New York officials are considering the use of a familial DNA search to get a lead on a suspect in the strangulation death of a runner.
NIH Director Francis Collins has selected a retired Army major general and cardiologist for the CEO spot at the agency's embattled Clinical Center.