renal cell carcinoma
Genomic Classifier for Kidney Cancer Recurrence Risk May Help Personalize Adjuvant Therapy
Sequencing of 12 cancer-related genes in clear-cell renal cell carcinoma samples identified combinations of somatic mutations that were linked to recurrence risk.
Cancer Genome Analysis Unearths Potentially Targetable Tandem Repeat Expansions
Investigators identified 160 recurrent repeat expansions in seven cancer types, including a kidney cancer-related expansion that appeared susceptible to a targeted treatment.
Kidney Cancer Study Links Checkpoint Immunotherapy Responses to T Cell Features
Researchers from the UK used integrated genomics to analyze prospectively collected samples from metastatic clear cell renal cell carcinoma patients.
Renal Cell Carcinoma Risk Gene Representation Can Vary With Ancestry
While risky variants in the FH gene were more common in renal cell carcinoma patients with African ancestry, European patients more often carried pathogenic CHEK2 gene changes.
Mutations in Mitochondrial DNA Underlie Certain Subtype of Aggressive Renal Cancer
The researchers said this new data could lead to the development of effective therapies for patients with hereditary leiomyomatosis and renal cell carcinoma.