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pulmonary arterial hypertension

Handful for PAH

A team of Cambridge researchers use sequencing to find gene mutations linked to pulmonary arterial hypertension, BBC News reports.

Co-discoverers of the link between the gene EIF2AK4 and specific types of pulmonary hypertension, Intermountain and ARUP are now collaborating to offer clinical testing.

NEW YORK (GenomeWeb News) – A team led by researchers at Columbia University Medical Center uncovered a new gene linked with pulmonary arterial hypertension, and as the group reported in The New England Journal of Medicine

EGEN announced this week that its microRNA inhibitor-based treatment for pulmonary arterial hypertension was able to reverse the pulmonary hypertension associated with advanced stages of the disease and restore cardiovascular function in rat models.

Miragen Therapeutics said this week that it has taken an exclusive license to intellectual property held by the University of Glasgow that is related to the use of microRNA-145 in the treatment of pulmonary arterial hypertension.
Terms of the deal were not disclosed.

The awards are part of NHLBI's newest proteomics program, which seeks to "understand the mechanisms that underlie many of the clinical questions related to heart, lung, and blood disease," said an official.

The nonprofit Biden Cancer Initiative is suspending its operations, according to the Associated Press.

Researchers examine how white nationalists handle personal genetic ancestry results that conflict with their racist worldview, the New York Times reports.

NPR speaks with research participants before and after they learn their APOE E4 status, which affects their risk of developing Alzheimer's disease.

In PLOS this week: genetic characterization of Toxoplasma gondii strains, Crimean-Congo Hemorrhagic Fever Virus uncovered in Sudan, and more.