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psychiatric conditions

Circular Genomics Readying to Launch Zoloft Response Diagnostic Based on Circular RNA Biomarker
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The findings from a recent biomarker study that identified responders and non-responders to the antidepressant will be incorporated into a product launch next year.

Circular Genomics Sees More Direct PGx Assay Through Brain-Derived Circular RNA
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The company sees a clearer path to clinical validation and reimbursement through molecules that more directly measure how drugs affect the brain.

Transcriptomic Data May Provide New Way to Classify, Compare Brain Disorders

The researchers studied gene expression of disease-related genes among neurotypical brains and found associations that were previously unknown.

Rare Single-Gene Variants Confer High Risk for Mental Health Conditions, Geisinger Study Shows
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Researchers suggest physicians should more routinely order genetic testing for patients with mental health disorders, a group that has historically been undertested.

Cross-Trait Meta-Analysis Explores Potential Pleiotropy Across Psychiatric Conditions

Researchers considered genetic overlap between pairs of psychiatric conditions and across 12 psychiatric disorders, highlighting evolutionarily conserved parts of the genome.

Nov 17, 2022

Non-Random Mating May Exaggerate Findings of Pleiotropy in Population Genetic Studies

Aug 24, 2022

Early-Onset Psychosis Linked to Enhanced CNV Burden

Jul 15, 2022

Insomnia Linked to Hundreds of Loci in GWAS Meta-Analysis

May 5, 2022

Modeling Study Reveals Genetic Architecture Across Psychiatric Conditions

Apr 6, 2022

Psychiatric Disease Blood Markers Proposed From Biochemical, GWAS Profiles

Oct 22, 2021

SUPER Psychosis Study Presented at ASHG Digs Into Relationships of Rare Variants, Phenotypes

Sep 7, 2021

Polygenic Risk Score Addition Does Not Improve Models Predicting Schizophrenia Prognosis

Jan 19, 2021

Psychiatric Disorder Risk Affected by Dysregulation of RNA-Binding Proteins

Feb 14, 2020

Genetic Study of Snoring Highlights Ties to Diverse Traits, Behaviors

Dec 12, 2019

Psychiatric Disorders Fall Into Groups With Shared Genetic Contributors in GWAS Meta-Analysis

Jul 29, 2019

Post-Traumatic Stress Disorder GWAS in Million Veteran Program Participants Identifies Risk Loci

May 23, 2019

Anxiety GWAS, Mouse Model Experiments Lead to Potential New Drug Target

Feb 25, 2019

Insomnia Studies Reveal New Risk Loci, Related Conditions

May 10, 2018

Myriad Pushes for Payor Coverage Based on GeneSight RCT Data
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Feb 28, 2017

Centers for Common Disease Genomics Program Standardizes Sequencing Analysis Pipeline
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Aug 3, 2016

Myriad to Acquire Psychiatry-Focused PGx Firm Assurex

May 12, 2016

CNSDose Assembling Psychiatric PGx Business Strategy Around Local Distribution Partners
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Feb 11, 2016

Team Taps Electronic Medical Records to Find Neanderthal Alleles Influencing Human Traits, Disease

Feb 4, 2016

New PGx Firm CNSDose to Launch Depression Drug Dosing Test
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Feb 3, 2016

Cofactor Genomics Acquires Narus Biotechnologies

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The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.