psychiatric conditions Circular Genomics Readying to Launch Zoloft Response Diagnostic Based on Circular RNA Biomarker Premium The findings from a recent biomarker study that identified responders and non-responders to the antidepressant will be incorporated into a product launch next year. Circular Genomics Sees More Direct PGx Assay Through Brain-Derived Circular RNA Premium The company sees a clearer path to clinical validation and reimbursement through molecules that more directly measure how drugs affect the brain. Transcriptomic Data May Provide New Way to Classify, Compare Brain Disorders The researchers studied gene expression of disease-related genes among neurotypical brains and found associations that were previously unknown. Rare Single-Gene Variants Confer High Risk for Mental Health Conditions, Geisinger Study Shows Premium Researchers suggest physicians should more routinely order genetic testing for patients with mental health disorders, a group that has historically been undertested. Cross-Trait Meta-Analysis Explores Potential Pleiotropy Across Psychiatric Conditions Researchers considered genetic overlap between pairs of psychiatric conditions and across 12 psychiatric disorders, highlighting evolutionarily conserved parts of the genome. Nov 17, 2022 Non-Random Mating May Exaggerate Findings of Pleiotropy in Population Genetic Studies Aug 24, 2022 Early-Onset Psychosis Linked to Enhanced CNV Burden Jul 15, 2022 Insomnia Linked to Hundreds of Loci in GWAS Meta-Analysis May 5, 2022 Modeling Study Reveals Genetic Architecture Across Psychiatric Conditions Apr 6, 2022 Psychiatric Disease Blood Markers Proposed From Biochemical, GWAS Profiles Oct 22, 2021 SUPER Psychosis Study Presented at ASHG Digs Into Relationships of Rare Variants, Phenotypes Sep 7, 2021 Polygenic Risk Score Addition Does Not Improve Models Predicting Schizophrenia Prognosis Jan 19, 2021 Psychiatric Disorder Risk Affected by Dysregulation of RNA-Binding Proteins Feb 14, 2020 Genetic Study of Snoring Highlights Ties to Diverse Traits, Behaviors Dec 12, 2019 Psychiatric Disorders Fall Into Groups With Shared Genetic Contributors in GWAS Meta-Analysis Jul 29, 2019 Post-Traumatic Stress Disorder GWAS in Million Veteran Program Participants Identifies Risk Loci May 23, 2019 Anxiety GWAS, Mouse Model Experiments Lead to Potential New Drug Target Feb 25, 2019 Insomnia Studies Reveal New Risk Loci, Related Conditions May 10, 2018 Myriad Pushes for Payor Coverage Based on GeneSight RCT Data Premium Feb 28, 2017 Centers for Common Disease Genomics Program Standardizes Sequencing Analysis Pipeline Premium Aug 3, 2016 Myriad to Acquire Psychiatry-Focused PGx Firm Assurex May 12, 2016 CNSDose Assembling Psychiatric PGx Business Strategy Around Local Distribution Partners Premium Feb 11, 2016 Team Taps Electronic Medical Records to Find Neanderthal Alleles Influencing Human Traits, Disease Feb 4, 2016 New PGx Firm CNSDose to Launch Depression Drug Dosing Test Premium Feb 3, 2016 Cofactor Genomics Acquires Narus Biotechnologies Load More Breaking News NanoString, A*Star, Next Level Genomics to Launch Spatial Biology Laboratory in Singapore FDA Approves Entrogen's RAS Mutation Detection Kit as CDx for Vectibix Cancer Predisposition Variants Increase Secondary Cancer Mortality Risk in Pediatric Survivors BostonGene, Johns Hopkins University Partner for Multiple Cancer Clinical Research Projects KromaTid, Noble Life Sciences Ink Distribution, OEM Agreement The Scan Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. Small Study of Gene Editing to Treat Sickle Cell Disease In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema. Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.