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With the help of electronic health record data, researchers searched for common variants linked to hundreds of diseases or clinical lab measurements.

This Week in PLOS

In PLOS this week: ramifications of sexual recombination in bacteria, Mycobacterium leprae genome sequences, and more.

The researchers also applied their database to impute alleles in the region linked to psoriasis.

Researchers delved into the roots of psoriasis using genome-wide association study data for almost 35,000 European or Chinese individuals with or without the condition.

In a genome-wide meta-analysis, an international team examined loci linked to both atopic dermatitis and psoriasis, but with differing effects on the disorders.

NEW YORK (GenomeWeb) – In a study appearing online today in Science Translational Medicine, researchers from Germany, the UK, and Italy described skin gene expression shifts that correspond to the presence of psoriasis or eczema — conditions that can be tricky to tell apart.

A team of Spanish researchers this week published a new report implicating microRNA-21 in psoriasis and demonstrating that 8-mer locked nucleic acids targeting the miRNA could improve symptoms of the disease in a mouse model.

NEW YORK (GenomeWeb News) – Low-frequency variants in protein-coding portions of the genome may make relatively modest contributions to psoriasis risk, according to an exome sequencing-based association stu

NEW YORK (GenomeWeb News) – The National Institute of Arthritis and Musculoskeletal and Skin Diseases plans to fund research that will use data from genome-wide association studies to discover genes and variants that influence the risk for certain diseases, according to a new funding announcement

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Researchers tie a variant in ADAMTS3 to breathing difficulties in dissimilar dog breeds, according to Discover's D-brief blog.

The Japan Times reports that researchers sequenced the genome of a woman who lived during the Jomon period.

Parents of children with rare genetic disease have to contend with shifts in the interpretation of genetic variants, the Wall Street Journal reports.

In Science this week: single-nucleus RNA sequencing of brain tissue from individuals with autism, and more.