psoriasis

With the help of electronic health record data, researchers searched for common variants linked to hundreds of diseases or clinical lab measurements.

This Week in PLOS

In PLOS this week: ramifications of sexual recombination in bacteria, Mycobacterium leprae genome sequences, and more.

The researchers also applied their database to impute alleles in the region linked to psoriasis.

Researchers delved into the roots of psoriasis using genome-wide association study data for almost 35,000 European or Chinese individuals with or without the condition.

In a genome-wide meta-analysis, an international team examined loci linked to both atopic dermatitis and psoriasis, but with differing effects on the disorders.

NEW YORK (GenomeWeb) – In a study appearing online today in Science Translational Medicine, researchers from Germany, the UK, and Italy described skin gene expression shifts that correspond to the presence of psoriasis or eczema — conditions that can be tricky to tell apart.

A team of Spanish researchers this week published a new report implicating microRNA-21 in psoriasis and demonstrating that 8-mer locked nucleic acids targeting the miRNA could improve symptoms of the disease in a mouse model.

NEW YORK (GenomeWeb News) – Low-frequency variants in protein-coding portions of the genome may make relatively modest contributions to psoriasis risk, according to an exome sequencing-based association stu

NEW YORK (GenomeWeb News) – The National Institute of Arthritis and Musculoskeletal and Skin Diseases plans to fund research that will use data from genome-wide association studies to discover genes and variants that influence the risk for certain diseases, according to a new funding announcement

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The World Health Organization has announced the members of its gene-editing committee, according to NPR.

DARPA is working on developing algorithms that gauge the credibility of research findings, Wired reports.

The American Society of Breast Surgeons recommends all women diagnosed with breast cancer be offered genetic testing, the Washington Post says.

In Science this week: comparison of modern, historical rabbit exomes uncovers parallel evolution after myxoma virus exposure; and more.