psoriasis

With the help of electronic health record data, researchers searched for common variants linked to hundreds of diseases or clinical lab measurements.

This Week in PLOS

In PLOS this week: ramifications of sexual recombination in bacteria, Mycobacterium leprae genome sequences, and more.

The researchers also applied their database to impute alleles in the region linked to psoriasis.

Researchers delved into the roots of psoriasis using genome-wide association study data for almost 35,000 European or Chinese individuals with or without the condition.

In a genome-wide meta-analysis, an international team examined loci linked to both atopic dermatitis and psoriasis, but with differing effects on the disorders.

NEW YORK (GenomeWeb) – In a study appearing online today in Science Translational Medicine, researchers from Germany, the UK, and Italy described skin gene expression shifts that correspond to the presence of psoriasis or eczema — conditions that can be tricky to tell apart.

A team of Spanish researchers this week published a new report implicating microRNA-21 in psoriasis and demonstrating that 8-mer locked nucleic acids targeting the miRNA could improve symptoms of the disease in a mouse model.

NEW YORK (GenomeWeb News) – Low-frequency variants in protein-coding portions of the genome may make relatively modest contributions to psoriasis risk, according to an exome sequencing-based association stu

NEW YORK (GenomeWeb News) – The National Institute of Arthritis and Musculoskeletal and Skin Diseases plans to fund research that will use data from genome-wide association studies to discover genes and variants that influence the risk for certain diseases, according to a new funding announcement

Pages

American scientists find themselves once again warning the Trump administration not to dismiss science, the New Yorker report.

A new study suggests CRISPR could be used to save coral reefs from dying off, Forbes reports.

Researchers have found that the i-motif shape of DNA previously observed in the lab also exists in human cells, and that it may serve a purpose.

In PNAS this week: a genomic, transcriptomic, and metabolomic analysis of the tea plant, Arabidopsis thaliana's adaptations to specific local environments, and more.