Pseudomonas Cystic Fibrosis Sinus Infections Involve Microbes With Shifting Evolution Patterns While early-stage Pseudomonas aeruginosa sinus infections were marked by selection for aggregating forms of the bug, genetic drift and genome degradation arose later in infection. Curetis Receives €350K German Government Grant to Develop Carbapenem Resistance Test The project, coordinated by Jena University Hospital and expected to run for five years, aims to address resistance mechanisms in Gram-negative pathogens. Signature Science Gets CDC Contract to Evaluate Molecular Microbial Detection Methods Signature Science will assess the validity of metagenomic and metatranscriptomic analyses to detect the transmission of viable pathogens in healthcare settings. IDbyDNA, Locus Biosciences Partner on CDx for CRISPR Antimicrobial The next-generation sequencing test will be used to select patients for a clinical trial of Locus' Pseudomonas aeruginosa antimicrobial product. Cepheid, MedImmune, COMBACTE Ink Bacterial Dx Collaboration Cepheid will create Xpert cartridge tests to detect S. aureus and P. aeuginosa, to be used in clinical trials for biologics intended to prevent pneumonia. Aug 28, 2015 Team Characterizes Mango Pathogen With Genome Sequencing, Comparative Genomics Feb 27, 2009 Community-Bred GO Terms Aimed to Help Scientists Manage Microbe-Host Interactions Premium Feb 17, 2009 Papers of Note for Jan 2009 Premium Feb 3, 2009 AdvanDx Gets FDA OK for Dual Pathogens Test Breaking News Drugs to Treat Smoking Addiction Suggested by Multi-Ancestry Transcriptome-Wide Association Study Chromosome 22 Copy Number Variants Linked to Traits in General Population Unilabs, Ambry Genetics Partner to Market Research-Use Genomic Testing Services Internationally Renalytix, Partners Launch $10M Consortium to Develop Kidney Disease Drug Response Tests PlumCare RWE Taps Lifebit to Scale Rady-Backed Newborn Sequencing Screening Program in Greece The Scan Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine. Family Genetic Risk Score Linked to Diagnostic Trajectory in Psychiatric Disorders Researchers in JAMA Psychiatry find ties between high or low family genetic risk scores and diagnostic stability or change in four major psychiatric disorders over time. Study Questions Existence of Fetal Microbiome A study appearing in Nature this week suggests that the reported fetal microbiome might be the result of sample contamination. Fruit Fly Study Explores Gut Microbiome Effects on Circadian Rhythm With gut microbiome and gene expression experiments, researchers in PNAS see signs that the microbiome contributes to circadian rhythm synchronicity and stability in fruit flies.