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Prostate Cancer

News and reporting on prostate cancer.

Using the strategy, which is under development as a biomarker discovery platform at ETH Zurich spin-off firm ProteoMedix, the researchers have identified four protein biomarkers tied to prostate cancer.

By sequencing the genomes of seven tumor-normal pairs, researchers have identified mutations and rearrangements that tend to crop up in multiple prostate cancer samples.

Characterized by the co-expression of three surface marker proteins – TRA-1-60, CD151, and CD166 – the cells offer insights into the molecular basis of human prostate cancer and suggest potential new therapeutic and biomarker strategies for the disease, said one of the scientists.

Tang and colleagues from Mirna Therapeutics reported that the microRNA miR-34a inhibits prostate cancer stem cells, as well as metastasis, in tumor-bearing animal models of the disease.

The firm also said that Israeli insurance firm Clalit has agreed to provide reimbursement for the Oncotype Dx colon cancer test.

The patent follows on one the company received last year for the Erenna platform itself, and comes as it begins efforts to develop the assay as a clinical diagnostic that it hopes to submit for US Food and Drug Administration approval within the next two years.

Through genome-wide association and replication studies involving tens of thousands of men, researchers from Decode Genetics and elsewhere have identified prostate specific antigen-associated genetic loci that they say may improve the accuracy of PSA-based prostate cancer screening.

The company said it has identified nearly 300 genes linked to prostate cancer recurrence in men who have had a previous radical prostatectomy.

Veridex has received rights to use certain DNA methylation biomarkers for colorectal cancer and prostate cancer screening.

The Vancouver Prostate Centre will use funding from Genome BC to conduct computational chemogenomic screening of compounds in a search for new prostate cancer treatments.


Nobel laureates and scientific societies urge NIH and the Department of Health and Human Services to revisit the recent decision to end funding for a coronavirus grant.

Bloomberg reports that BGI's SARS-CoV-2 testing sites in the Middle East have raised concerns among US officials.

A new Pew Research Center poll finds confidence in medical researchers has grown among US adults since the start of the coronavirus pandemic.

In Science this week: machine learning algorithm for faster Mendelian disorder diagnoses, gene linked to safe response to nitrogen-containing bisphosphonates, and more.