The study generated a number of three-protein panels that identified women at risk of giving birth preterm with sensitivity and specificity of above 80 percent.
According to one physician familiar with the test, it is a much needed diagnostic tool, but without insurance coverage it is too expensive for wide use.
Published this week in AJOG, the study found that the test could predict delivery before 37 weeks with 75 percent sensitivity and 74 percent specificity.
In a recent study, a pair of proteins identified women who went on to deliver preterm with specificity and sensitivity of 78 and 80 percent, respectively.
The mass spec-based proteomic test identified women who gave birth at or before 35 weeks gestation with an area under the receiver operating curve of .93.
Cincinnati Children's Hospital Medical Center researchers have uncovered gene expression changes associated with fetal maturity.
This fall the company is rolling out a limited commercial launch of the MRM mass spectrometry-based proteomic test, with a broader launch to come next year.
Members of the small hunter-gatherer group from sub-Saharan Africa carry killer-cell immunoglobulin-like receptor alleles that appear to alter immune function in ways that benefit pregnancy.
In PNAS this week: role for metabolomics in personalized medicine, vaginal microbiome shift linked to preterm birth, and more.
The company has identified 18 proteins that appeared useful in predicting a woman's risk of preterm delivery and aims to winnow that down to a set of eight to 12.
In PNAS this week: miR-515 levels higher in women with preeclampsia, horizontal gene transfer in parasitic plants, and more.
A cancer researcher retracts 19 articles from one journal for image manipulation, according to Retraction Watch.
Precision medicine has to consider context in addition to genetic mutations in cancer treatment, Medscape reports.
Genomics may help the Cavendish banana from succumbing to fungal infections, a trio of researchers writes at the Conversation.