Researchers profiled the composition and gene content of microbial communities in mouth, gut, and vaginal samples collected from 10 pregnant women.
Investigators identified candidate protein markers from aptamer-based proteomic profiles of samples from women with or without late-onset preeclampsia.
In Nature this week: fetal variants influence maternal risk of preeclampsia, and more.
A genome-wide association study of children whose mothers had preeclampsia, conducted as part of the InterPregGen study, implicates variants near the FLT1 gene in the condition.
The planned test will be based on LifeCodexx's methylation-specific quantitative PCR technology.
In PNAS this week: miR-515 levels higher in women with preeclampsia, horizontal gene transfer in parasitic plants, and more.
Using absolute and relative gene expression analyses, researchers identified expression patterns associated with preeclampsia in dozens of placental tissue samples.
The money will be used to complete development of the preeclampsia test PrePsia and to commercialize an in-licensed metabolomic biomarker technology.
Roche's molecular diagnostics business, which makes up 17 percent of its overall diagnostics sales, grew 11 percent, driven by virology testing and sequencing.
The prospective study found the markers were able to rule out a woman's chance of developing preeclampsia with a negative predictive value of 99.3 percent.
Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.
The Wall Street Journal looks into the cost of new gene therapies.
An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.
In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.