Plasmodium Gene Screen Leads to Potential Malaria Targets in Liver-Stage Plasmodium Parasites Sequencing and other experiments on barcoded Plasmodium berghei mutant strains helped researchers narrow in on key metabolic pathways in the parasite's liver stage. Malaria Drug Resistance Genetic Features Profiled in Southeast Asia Researchers used genomic and transcriptomic data of isolates from seven Southeast Asian countries to find resistance-relevant pathways and expression quantitative trait loci. Researchers Explore Population Patterns in Zoonotic Malaria Parasite Three genetically distinct sub-populations appeared when the team sequenced and compared 48 clinical isolates of Plasmodium knowlesi and five lab lines. Malaria GWAS Uncovers Protective Locus A chromosome 4 locus near glycophorin-coding genes appears to decrease the risk of severe malaria in African children, particularly those from East Africa. U of Maryland-led Statistical Study Points to Co-evolution of Plasmodium Parasite, Mammalian Hosts Premium The results showed that mammalian-infecting Plasmodium evolved contemporaneously with their hosts, with little evidence of parasite host-switching on an evolutionary scale. Jun 27, 2013 EU-Funded Consortium Looks to Move Blood-based, Lateral Flow Malaria MDx to Commercial Development Premium Mar 14, 2013 CDC Scientists Develop 'PET-PCR' Fluorogenic Primers to Enable Inexpensive Field-Based Malaria MDx Premium Apr 8, 2010 CDC Researchers Verify 'Nested' PCR Assay as Gold Standard for Malaria Dx Premium Jan 14, 2010 UK Team Develops Genetic Map for Plant Used In Malaria Treatment Breaking News Pediatric Cardiomyopathy Exome Sequencing Study Suggests More Disease Genes to be Found People in the News: New Appointments at Helix, Pacific Biosciences, SomaLogic, More New Products Posted to GenomeWeb: Amoy Diagnostics, Akoya Biosciences, Congenica, Lucence In Brief This Week: BGI, Gencove, Cepheid, Biocartis, Biognosys, Co-Diagnostics, More Florida Lab Owner Pleads Guilty to $6.9M COVID-19 False Billing Scheme Pacific Biosciences Outlines Progress on Short-Read Sequencing at JPM, Partners With Canexia Health The Scan Close Panel Vote on Califf Nomination The New York Times reports there was a close committee vote to advance the nomination of Robert Califf to lead the US Food and Drug Administration to the full Senate. Task Force Reports on Scientific Integrity Nature News writes that that a new task force report recommends that the US establish a cross-agency scientific integrity council. Across the Hall Genetic testing, closed-circuit cameras, and more show how a traveler, without any contact, infected others at a New Zealand quarantine facility, CNN reports. Science Paper Examines Influence of Chromatin Modifications on Obsessive-Compulsive Disorder In Science this week: genes regulating chromatin modification may contribute to OCD risk.