This Week in Cell

In Cell this week: functional profiling of Plasmodium genome, a self-inactivating rabies virus, and more.

This Week in PLOS

In PLOS this week: RNA-seq, ChIP-seq to determine metformin response; array-based approach to detect protozoa in blood; and more.

Three genetically distinct sub-populations appeared when the team sequenced and compared 48 clinical isolates of Plasmodium knowlesi and five lab lines.

A chromosome 4 locus near glycophorin-coding genes appears to decrease the risk of severe malaria in African children, particularly those from East Africa.

The results showed that mammalian-infecting Plasmodium evolved contemporaneously with their hosts, with little evidence of parasite host-switching on an evolutionary scale.

A public-private consortium formed to investigate multi-drug resistance in malaria this week reached the end of a five-year, €2.8 million (about $3.6 million) project having identified a number of genetic markers related to drug resistance and developed a highly sensitive and spe

This article has been updated from a previous version to correct the name and title of an interview subject.

Scientists from the US Centers for Disease Control determined that a so-called "nested" PCR assay is more effective than easier-to-perform semi-nested or single-tube multiplex PCR assays for detecting Plasmodium, the parasite that causes malaria.

An opinion piece in the Guardian argues that President Donald Trump is uninterested in science and that might not be a bad thing for the field.

The San Francisco Chronicle reports the Veterans Affairs Health System is studying whether genetic testing can help prescribe better depression therapies.

Stat News reports that Spark Therapeutics' Luxturna is now being used to treat a wider array of patients.

In Genome Biology this week: transcription factor use among brittle stars, single-cell RNA sequencing strategy, and more.