Plasmodium
Gene Screen Leads to Potential Malaria Targets in Liver-Stage Plasmodium Parasites
Sequencing and other experiments on barcoded Plasmodium berghei mutant strains helped researchers narrow in on key metabolic pathways in the parasite's liver stage.
Malaria Drug Resistance Genetic Features Profiled in Southeast Asia
Researchers used genomic and transcriptomic data of isolates from seven Southeast Asian countries to find resistance-relevant pathways and expression quantitative trait loci.
Researchers Explore Population Patterns in Zoonotic Malaria Parasite
Three genetically distinct sub-populations appeared when the team sequenced and compared 48 clinical isolates of Plasmodium knowlesi and five lab lines.
Malaria GWAS Uncovers Protective Locus
A chromosome 4 locus near glycophorin-coding genes appears to decrease the risk of severe malaria in African children, particularly those from East Africa.
U of Maryland-led Statistical Study Points to Co-evolution of Plasmodium Parasite, Mammalian Hosts
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The results showed that mammalian-infecting Plasmodium evolved contemporaneously with their hosts, with little evidence of parasite host-switching on an evolutionary scale.