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pediatric cancer

The funds from the Sohn Conference Foundation will allow the university to provide sequencing analysis and expertise to kids with cancer to hospitals in the city.

With ProteinPaint, investigators can visualize sequence mutations, gene fusions, and RNA expression to interpret patterns in germline and tumor samples.

More than 8 percent of pediatric cancer cases considered by the Pediatric Cancer Genome Project carried mutations affecting established cancer risk genes. 

Exome and targeted gene sequencing uncovered germline variations in the ETV6 gene that may increase susceptibility to acute lymphoblastic leukemia.

A five-gene signature was linked to both event-free survival and overall survival in individuals with a type of rhabdomyosarcoma missing a prognostically informative gene fusion.

UC Santa Cruz is collaborating with Microsoft's research arm to use Azure to analyze data from several genomics projects focused on pediatric cancer and other diseases.

Researchers performed exome and transcriptome sequencing in 91 pediatric cancer patients, identifying actionable results in 42 patients.

Using funds from the California precision medicine initiative, the group will use its bioinformatics expertise to match patients to treatments in pediatric clinical trials.

The initiative aims to integrate clinical, genomic, environmental, and other data from patients to help determine disease mechanisms and develop precise therapies.

An international team detected a variant associated with anthracycline-induced cardiotoxicity in a study of more than 450 children treated with the drug.

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A bill passed by a US House of Representatives appropriations subcommittee would give scientific agencies including the National Science Foundation boosts in funding.

University of Idaho researchers model the scientific discovery process to examine the link between reproducibility and scientific truth.

Relocating USDA agencies outside of Washington, DC, may make them less effective, critics of the move tell NPR.

In PLOS this week: genes that help Borrelia burgdorferi survive in ticks, CiliaCarta collection of about 1,000 suspected cilia genes, and more.