Pediatric Cancer News and reporting on pediatric cancer. Childhood Brain Tumors in Crosshairs of New CHOP-led Sequencing Biobank Effort Premium Investigators from the hospital's D3b program are leading development of what aims to be the largest clinically annotated pediatric brain tumor cohort study to date. Germline Cancer Risk Genes May Hold Rhabdomyosarcoma Survival Clues, Study Suggests Research presented at ASHG suggested that germline cancer susceptibility profiling may help to predict survival outcomes for a subset of rhabdomyosarcoma cases. Analysis Finds Sibling Cascade Testing Could Be Cost Effective in Pediatric Cancer The analysis also found that about half the sibling deaths due to cancer could be averted by surveillance following cascade testing, as compared to usual care. Molecular Profiling in Pediatric Cancer Trials Continues to Prove Valuable for Treatment Matching Premium The GAIN/iCat2 study and the Pediatric MATCH trial showed that molecular data has a significant impact on treatment recommendations for kids with cancer. TGen-Led Team Spots Pediatric, Pancreatic Cancer From cfDNA Fragments in Urine Premium The liquid biopsy method analyzes fragment ends within recurrently protected regions in cell-free DNA from a patient's urine sample. Feb 16, 2021 MSK Team Explores Clinical Utility of Germline Testing for Pediatric Cancer Patients Dec 8, 2020 Genetic Loci Influence Risk of Cardiomyopathy in Pediatric Cancer Survivors of African Ancestry Dec 7, 2020 Neuroblastoma Super Enhancer Profiles Pinpoint Four Epigenetic Subtypes Nov 25, 2020 Pediatric Brain Tumor Proteomics Highlight Possible Treatment Targets, Biomarkers Oct 27, 2020 SickKids' 'Rigorous' Molecular Analysis IDs Targetable Alterations, Cancer Susceptibility Mutations Premium Oct 6, 2020 Pediatric Cancer Program Uses Comprehensive Molecular Profiling to Match Patients to Therapies Sep 16, 2020 Startup Stitch Bio Bets on CRISPR Tech to Render Cancer Cells With Gene Fusions Druggable Premium Aug 11, 2020 Childhood Ependymoma Single-Cell Sequencing Study Reveals New Cellular Subpopulations Aug 7, 2020 Computational Tool Analyzes Noncoding Mutations to Classify Cancer Subtypes Premium Jun 24, 2020 Nationwide Children's Reports High Diagnostic Yield of Combined DNA, RNA Analysis in Pediatric Cancers Jun 5, 2020 Secondary Tumor Risk in Pediatric Cancer Survivors Linked to Germline Variants, Treatment Type Jun 2, 2020 Seven Bridges Joins International Genomic Cancer Research Effort May 30, 2020 Pediatric Precision Oncology Study Matches 28 Percent of Patients to Targeted Therapies May 6, 2020 Pediatric Cancer Patients With Solid Tumors Have Many Druggable Germline Alterations Apr 16, 2020 Human Tumor Atlas Network Team Shares Strategy for Tracking Tumor Transitions Apr 13, 2020 Pediatric Low-Grade Glioma Molecular and Clinical Analysis Defines Subtypes That Predict Outcome Apr 2, 2020 Cancer Researchers Discover Novel Inherited Mutation Predisposing Children to Medulloblastoma Jan 30, 2020 Jackson Lab, Shriners Hospitals to Study Genetics of Pediatric Orthopedic Disorders Dec 19, 2019 Blood-Based Sequencing Test Identifies Pediatric Cancer Infections Before Symptoms Dec 16, 2019 Neuroblastoma Study Reveals Rearrangements Originating From Extrachromosomal Circular DNA Load More Breaking News New Approach Identifies Candidate Causal Variants for Neuropsychiatric, Neurodevelopmental Conditions People in the News: Baylor's Thomas Caskey Dies; New Appointments at UK Biobank, CS Genetics, More In Brief This Week: Pathogenomix, Uniogen, Genetic Technologies, DnaNudge, Gravity Diagnostics, More New Products Posted to GenomeWeb: Biodesix, Curio Genomics, Akoya Biosciences, More NIH Earmarks $170M for All of Us Program's Personalized Nutrition Study Taiwanese Firm's IP Asserted in Suit Against Pacific Biosciences Found Partially Unpatentable The Scan Omicron's Sewage Path The New York Times writes that testing sewage is helping public health officials track Omicron. IBM Sells Part of Watson Health The Wall Street Journal reports IBM is selling part of its Watson Health business to an investment firm. Identifying the Right Whales The Boston Globe writes that genetic testing has helped identify North American right whales and find that weaning can take place earlier than thought. Science Papers on Approach to Quickly Sort Single Cells, Alternative Splicing in Cancer In Science this week: high-speed sorting of single cells using fluorescence imaging, and more.