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Pediatric Cancer

News and reporting on pediatric cancer.

Molecular Profiling in Pediatric Cancer Trials Continues to Prove Valuable for Treatment Matching
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The GAIN/iCat2 study and the Pediatric MATCH trial showed that molecular data has a significant impact on treatment recommendations for kids with cancer.

TGen-Led Team Spots Pediatric, Pancreatic Cancer From cfDNA Fragments in Urine
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The liquid biopsy method analyzes fragment ends within recurrently protected regions in cell-free DNA from a patient's urine sample.  

MSK Team Explores Clinical Utility of Germline Testing for Pediatric Cancer Patients

The researchers found that 18 percent of pediatric cancer patients tested with MSK-IMPACT harbored one or more inherited risk mutation.

Genetic Loci Influence Risk of Cardiomyopathy in Pediatric Cancer Survivors of African Ancestry

Researchers uncovered genetic loci that may influence why childhood cancer survivors of African ancestry are more likely to develop therapy-linked cardiomyopathy.

Neuroblastoma Super Enhancer Profiles Pinpoint Four Epigenetic Subtypes

Using a combination of genomic and epigenomic profiling, researchers spelled out super enhancer-based subtypes, including one linked to poor clinical outcomes.

Nov 25, 2020

Pediatric Brain Tumor Proteomics Highlight Possible Treatment Targets, Biomarkers

Oct 27, 2020

SickKids' 'Rigorous' Molecular Analysis IDs Targetable Alterations, Cancer Susceptibility Mutations
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Oct 6, 2020

Pediatric Cancer Program Uses Comprehensive Molecular Profiling to Match Patients to Therapies

Sep 16, 2020

Startup Stitch Bio Bets on CRISPR Tech to Render Cancer Cells With Gene Fusions Druggable
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Aug 11, 2020

Childhood Ependymoma Single-Cell Sequencing Study Reveals New Cellular Subpopulations

Aug 7, 2020

Computational Tool Analyzes Noncoding Mutations to Classify Cancer Subtypes
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Jun 24, 2020

Nationwide Children's Reports High Diagnostic Yield of Combined DNA, RNA Analysis in Pediatric Cancers

Jun 5, 2020

Secondary Tumor Risk in Pediatric Cancer Survivors Linked to Germline Variants, Treatment Type

Jun 2, 2020

Seven Bridges Joins International Genomic Cancer Research Effort

May 30, 2020

Pediatric Precision Oncology Study Matches 28 Percent of Patients to Targeted Therapies

May 6, 2020

Pediatric Cancer Patients With Solid Tumors Have Many Druggable Germline Alterations

Apr 16, 2020

Human Tumor Atlas Network Team Shares Strategy for Tracking Tumor Transitions

Apr 13, 2020

Pediatric Low-Grade Glioma Molecular and Clinical Analysis Defines Subtypes That Predict Outcome

Apr 2, 2020

Cancer Researchers Discover Novel Inherited Mutation Predisposing Children to Medulloblastoma

Jan 30, 2020

Jackson Lab, Shriners Hospitals to Study Genetics of Pediatric Orthopedic Disorders

Dec 19, 2019

Blood-Based Sequencing Test Identifies Pediatric Cancer Infections Before Symptoms

Dec 16, 2019

Neuroblastoma Study Reveals Rearrangements Originating From Extrachromosomal Circular DNA

Nov 25, 2019

Pediatric Brain Cancer Clues Drawn From Developing Brain Cell Transcriptomes

Oct 25, 2019

Treatment Targets Identified by RNA Sequencing in Pediatric Cancer Cases

Aug 7, 2019

Pediatric Cancer Researchers, Clinicians Look to Enhance Molecular Data Collection, Distribution

Breaking News
The Scan

Billions for Antivirals

The US is putting $3.2 billion toward a program to develop antivirals to treat COVID-19 in its early stages, the Wall Street Journal reports.

NFT of the Web

Tim Berners-Lee, who developed the World Wide Web, is auctioning its original source code as a non-fungible token, Reuters reports.

23andMe on the Nasdaq

23andMe's shares rose more than 20 percent following its merger with a special purpose acquisition company, as GenomeWeb has reported.

Science Papers Present GWAS of Brain Structure, System for Controlled Gene Transfer

In Science this week: genome-wide association study ties variants to white matter stricture in the brain, and more.