The study showed that targeted sequencing was feasible, identified many clinically relevant alterations, and directed effective targeted therapy in several cases.
Under the PIPseq program, Columbia University researchers sequenced the exome, transcriptome, or a gene panel in tumors of 101 high-risk pediatric cancer patients.
The researchers found that 80 percent of pediatric posterior fossa ependymomas have decreased levels of H3K27me3 histone modifications.
NantHealth, CHOP, and their collaborators intend to release genomic, transcriptomic, and proteomic data from 1,600 patients in the next six months
BC Cancer Agency researcher Marco Marra presented preliminary lessons from a cancer genome- and transcriptome-based trial underway in the province.
The partners will exchange all information they have on genetic mutations leading to cancer with an eye toward accelerating research and drug discovery efforts.
The grant from St. Baldrick's Foundation will be used to support UCSC's genomics and informatics Treehouse Childhood Cancer Initiative.
The protocol is currently being used to study Tecentriq and Cotellic in children, but Genentech wants to use it to evaluate drugs across its oncology portfolio.
The laboratory will employ dedicated computational biologists and bioinformaticians to analyze genomic datasets for ALSF-funded researchers and other scientists.
FedCentric also plans to offer a combined hardware and software solution as well as a cloud-based software option for genomics customers.
In Science this week: metagenomic-based technique for determining protein structure, and more.
An academic laments the rise of narcissism in the sciences, the Guardian reports.
Outgoing FDA commissioner Robert Califf writes in an editorial that the agency can help boost innovation.
The Trump transition team has asked NIH Director Francis Collins to remain at his post, though it's unclear for how long that will be.