pathogens

Researchers integrated results from a pathogen-host association study with available clinical data to find variants influencing both infection responses and other disease risks.

The firm is developing products based in part on DNA-enrichment and bioinformatics technologies developed at Stanford and Harvard, respectively.

Public health microbiologists are forging ahead with WGS, even as others caution that it may not yet be ready for such a role, said speakers at ASM Microbe 2018.

The firms plan to integrate Curetis' Unyvero sample prep system and MGI's NGS to create a microbial pathogens and antibiotic resistance detection workflow.

The firm has used its proximity ligation method to interpret metagenomic sequence data from a human fecal sample, unraveling new and known genomes in the mix. 

The firms will use MGI's sequencing technology and Curetis' sample prep platform and antibiotic resistance database to develop IVDs, initially for China.

Ares plans to use the GEAR database to discover new markers of antibiotic resistance and will eventually develop it as an interpretation service. 

Among other plans, CosmosID is using the funds to prep its platform for clinical use including running validation studies with partner hospitals.

Ötzi the Iceman

Researchers generated a near complete genome sequence for a 5,300 year old Helicobacter pylori strain found in the gut of Ötzi, the Tyrolean Iceman.

The researchers demonstrated that the panel could identify pathogens in mock clinical samples even at very low levels, while unbiased sequencing could not.

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A new study finds that a placental protein linked with preeclampsia can be targeted by RNA silencing, according to the New Scientist.

A settlement is expected in a Duke University lawsuit hinging on using falsified data to win grants, Retraction Watch and Science report.

In PNAS this week: approach for analyzing the expression of endogenous retroviruses, circular RNAs that influence host-virus interactions, and more.

A phylogenetic analysis finds that the rare hemimastigotes form their own supra-kingdom, CBC reports.