osteosarcoma

Researchers led by the Wellcome Trust Sanger Institute also reported that combined chromothripsis and amplification might be a driving mechanism of osteosarcoma.

The collaborators hope initial research in canines can be a proving ground for synthetic viruses designed to kill particular tumors, perhaps even in humans.

An Old Case of Cancer

South African researchers uncover bone cancer in an ancient hominin ancestor.

The study identified five SNPs significantly associated with five-year progression-free survival and defined risk groups with widely different risks of disease recurrence.

NEW YORK (GenomeWeb Daily News) – Bone cancer risk loci in dogs vary by breed, but a number overlap in pathways linked to bone formation and growth, researchers from Uppsala University and the Broad Institute reported in Genom

The researchers aim to find rearrangements in the small amounts of DNA that leak out from the bone cancer into the bloodstream.

The goal of the project is two-fold: the exome sequencing portion of the study will look for genes that underlie the genesis of the disease, while whole-genome sequencing of patients' plasma will be used to look for patient-specific rearrangements that could be used as the basis for a test.

"A key ethical question is, when you do this next-gen whole-genome sequencing, do you return that information back to the families and patients? A part of this project is to study that question," said Poul Sorensen of the BC Cancer Agency.

Consulting company McKinsey says diagnostics companies will have to combine genomic data analysis, electronic medical records, effective reimbursement strategies, and regulatory compliance in order to win.

A new report has found that researchers in Africa are still heavily dependent on funding from organizations in the US, Europe, and China, Nature News says.

An article in The Atlantic argues that the progress being made in science isn't keeping pace with the money and time being spent on research.

In Science this week: a CRISPR screen identifies sideroflexin 1 as a requisite component of one-carbon metabolism, and more.