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osteosarcoma

The authors of the study noted that these genetic findings could guide better clinical decisions for patients and improve outcomes.

The actual match rate is significantly higher than the 10 percent rate the researchers anticipated they would see when the study began in 2017.

Researchers led by the Wellcome Trust Sanger Institute also reported that combined chromothripsis and amplification might be a driving mechanism of osteosarcoma.

The collaborators hope initial research in canines can be a proving ground for synthetic viruses designed to kill particular tumors, perhaps even in humans.

An Old Case of Cancer

South African researchers uncover bone cancer in an ancient hominin ancestor.

The study identified five SNPs significantly associated with five-year progression-free survival and defined risk groups with widely different risks of disease recurrence.

NEW YORK (GenomeWeb Daily News) – Bone cancer risk loci in dogs vary by breed, but a number overlap in pathways linked to bone formation and growth, researchers from Uppsala University and the Broad Institute reported in Genom

The researchers aim to find rearrangements in the small amounts of DNA that leak out from the bone cancer into the bloodstream.

The goal of the project is two-fold: the exome sequencing portion of the study will look for genes that underlie the genesis of the disease, while whole-genome sequencing of patients' plasma will be used to look for patient-specific rearrangements that could be used as the basis for a test.

"A key ethical question is, when you do this next-gen whole-genome sequencing, do you return that information back to the families and patients? A part of this project is to study that question," said Poul Sorensen of the BC Cancer Agency.

Nature News reports on the US National Science Foundation's investigations of undisclosed foreign ties among researchers it funds.

Researchers have developed a set of 10 principles to guide how a list of all species on earth should be put together, the Guardian reports.

Wired reports on a new firm developing a gene writing approach for therapeutic genome changes.

In Nature this week: a method called cis-X combines whole-genome and transcriptome sequencing data to identify regulatory noncoding variants, and more.