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osteoporosis

This Week in Nature

In Nature this week: Yemen cholera epidemic bacteria sequenced, loci linked to osteoporosis, and more.

Using data for more than 500,000 individuals, researchers found 15 fracture-linked loci and saw genetic interactions between fracture and bone mineral density.

Using genotype and phenotype data from the UK Biobank project, a Stanford investigator uncovered variants linked to low bone mineral density.

More than 200 bone mineral density-linked loci turned up using data for over 140,000 individuals, including 153 new loci.

A genome-wide association study involving more than 20,000 individuals from Iceland uncovered new and known genetic associations with bone mineral density.

NEW YORK (GenomeWeb News) – The National Institute of Arthritis and Musculoskeletal and Skin Diseases plans to use up to $2.4 million next year to fund the creation of several core centers that will support scientists studying the underlying biology of muscle and bones and the range of disorders

Gen-Probe's Aptima HPV assay; Astra Biotech's osteoporosis test kit.

The researchers plan to compare differences in methylation patterns of 20 million CpG islands between pairs of twins. The aim is to find differences that explain why many identical twins do not develop the same diseases.

Under the Phenotypic Drug Discovery program, researchers from academia or biotech submit candidate compounds in specific therapeutic areas for Lilly to evaluate and profile. Participating organizations retain full IP rights to the compounds, but Lilly receives first rights to negotiate a broader collaboration or licensing agreement.

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Bloomberg reports that the DNA-for-cash deal reported in Kentucky might be a more widespread scam.

St. Jude Children's Research Hospital scientists have treated infants with X-linked severe combined immunodeficiency using gene therapy in an early phase study.

St. Louis Public Radio reports that some African Americans are turning to DNA ancestry testing to help guide genealogical searches.

In Nature this week: a genomic analysis of the snailfish Pseudoliparis swirei, ancient DNA analysis gives insight into the introduction of farming to England, and more.