osteoporosis Fauna Bio Gets $373K NIH Grant to Study Animal Genomes for Potential Drug Targets The company is studying hibernating animals to see if their genomes contain novel biological pathways that could be exploited to counteract complex human diseases. Genetic Study Explains Link Between Osteoporosis Drug, Cardiovascular Risk The findings underscore the value of carrying out large-scale human genetic analyses as part of drug target identification and validation efforts. Bone Mineral Density at Forefront in Genetic Fracture Risk Meta-Analysis Using data for more than 500,000 individuals, researchers found 15 fracture-linked loci and saw genetic interactions between fracture and bone mineral density. Bone Density GWAS Leads to New Loci, Osteoporosis Risk Score Using genotype and phenotype data from the UK Biobank project, a Stanford investigator uncovered variants linked to low bone mineral density. Bone Mineral Density GWAS Leads to New Loci With Potential Role in Osteoporosis More than 200 bone mineral density-linked loci turned up using data for over 140,000 individuals, including 153 new loci. Jan 6, 2016 Icelandic GWAS Reveals Variants Linked to Bone Mineral Density, Osteoporotic Fracture Risk Jan 24, 2013 NIAMS to Fund Research Cores for Musculoskeletal Conditions Apr 16, 2012 GWAS Meta-Analysis Finds Risk Variants for Osteoporosis-Related Bone Features and Fractures Dec 2, 2010 Dx Focus Dec 2, 2010: Clinical and Regulatory PCR and Nucleic Acid Testing News Premium Sep 7, 2010 TwinsUK and BGI to Study Epigenetics of 5,000 Twins under $30M Project Premium Aug 12, 2009 Lilly Readies Web Portal for PD2 Initiative; University of Cincinnati Joins List of Participants Premium Jul 1, 2009 Fate Therapeutics Licenses Stem-Cell Modulators for Bone Regeneration from UCLA Premium Apr 7, 2009 Short Reads: Apr 7, 2009 Premium Apr 2, 2009 MDRNA Sells Manufacturing Business to Par Pharmaceuticals to Hone RNAi Focus Premium Breaking News Imaging Mass Cytometry Discovers Tumor Microenvironment Features Predicting Lung Cancer Outcomes Metastatic Tumor Subtypes Found With Expression Profiling GenomeWeb Top 40 up 4 Percent in January, Following Broader Upswing LumiraDx Receives Notice From Nasdaq Over Missed Listing Requirement Sherlock Biosciences to Acquire Sense Biodetection The Scan Study Links Evolution of Longevity, Social Organization in Mammals With the help of comparative phylogenetics and transcriptomics, researchers in Nature Communications see ties between lifespan and social organization in mammals. Tumor Microenvironment Immune Score Provides Immunotherapy Response, Prognostic Insights Using multiple in situ analyses and RNA sequence data, researchers in eBioMedicine have developed a score associated with immunotherapy response or survival. CRISPR-Based Method for Finding Cancer-Associated Exosomal MicroRNAs in Blood A team from China presents in ACS Sensors a liposome-mediated membrane fusion strategy for detecting miRNAs carried in exosomes in the blood with a CRISPR-mediated reporter system. Drug Response Variants May Be Distinct in Somatic, Germline Samples Based on variants from across 21 drug response genes, researchers in The Pharmacogenomics Journal suspect that tumor-only DNA sequences may miss drug response clues found in the germline.