osteoarthritis

Using extensive genetic data from an Icelandic population, researchers identified two rare variants associated with osteoarthritis and related hip replacements.

The agreement is based on a jointly owned US patent application that claims methods of assessing a person's risk for generalized osteoarthritis based on IL-1 genotypes.

NEW YORK (GenomeWeb News) – The National Institute of Arthritis and Musculoskeletal and Skin Diseases plans to use up to $2.4 million next year to fund the creation of several core centers that will support scientists studying the underlying biology of muscle and bones and the range of disorders

NEW YORK (GenomeWeb News) – Researchers at the University of Miami School of Medicine plan to use a five-year, $2.5 million grant from the National Institute of Dental and Craniofacial Research to discover DNA variants that may function as biomarkers for susceptibility and therapeutic response fo

NEW YORK (GenomeWeb News) – The National Institute of Arthritis and Musculoskeletal and Skin Diseases plans to fund research that will use data from genome-wide association studies to discover genes and variants that influence the risk for certain diseases, according to a new funding announcement

A Novartis spokesperson told Pharmacogenomics Reporter last week that the company "plans to have discussions with the FDA about the specific requirements for the approval of lumiracoxib when used in conjunction with a biomarker program."

A Novartis official suggested that the resubmission of lumiracoxib could be the "first example" of a molecular diagnostic-based "drug rescue" in the industry.

The pharmaceutical firm will have access to GeneNews' genomic biomarker program.

Navigenics’ lower-priced program to incorporate genetic risk data in patients’ annual medical checkup raises questions as to whether personal genomics firms should be broadly marketing their services to physicians.

Technology Review reports that researchers in the US have used CRISPR to modify a number of human embryos.

By introducing genes from butterfly peas and Canterbury bells, researchers in Japan have developed a blue chrysanthemum, according to NPR.

Plant researchers plan to sequence some 10,000 samples that represent the major plant clades, ScienceInsider reports.

In Nature this week: a Danish reference genome, and more.