osteoarthritis
Type 2 Diabetes, Osteoarthritis Comorbidity Traced to Obesity-Related Processes
Researchers turned to genotyping, multiomics, and functional studies to untangle the processes contributing to type 2 diabetes and hip/knee osteoarthritis.
Serum Protein Biomarkers Can Predict Worsening Knee Osteoarthritis
The researchers said that being able to predict who is at risk of knee osteoarthritis progression will aid in the development of new treatments.
Osteoarthritis-Associated Variants in Retinoic Acid Synthesis Gene Point to Potential Treatment
A new study found that a drug that blocks retinoic acid metabolism could suppress mechano-inflammation in animal models of osteoarthritis.
New Osteoarthritis Genetic Risk Loci Uncovered in Multi-Ancestry Analyses
Researchers tracked down osteoarthritis-associated loci, along with related biological pathways, using data for nearly 484,400 Million Veteran Program and UK Biobank participants.
Osteoarthritis GWAS Leads to Key Genes, Treatment Targets
With a genome-wide association study and functional follow-up analyses, investigators saw 100 osteoarthritis-related loci including variants in potentially targetable genes and pathways.