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A number of the genes implicated are also the targets of approved therapeutics or of ones under testing.

In Nature this week: genomic and other analyses suggest the plant used to make chocolate was domesticated earlier and in a different region than previously thought, and more.

The researchers noted ties between osteoarthritis-linked variants and height, and found one risk loci that implicated the Hedgehog signaling pathway.

The researchers also found that genes located near these loci were differentially expressed in healthy versus diseased cartilage.

Using extensive genetic data from an Icelandic population, researchers identified two rare variants associated with osteoarthritis and related hip replacements.

The agreement is based on a jointly owned US patent application that claims methods of assessing a person's risk for generalized osteoarthritis based on IL-1 genotypes.

NEW YORK (GenomeWeb News) – The National Institute of Arthritis and Musculoskeletal and Skin Diseases plans to use up to $2.4 million next year to fund the creation of several core centers that will support scientists studying the underlying biology of muscle and bones and the range of disorders

NEW YORK (GenomeWeb News) – Researchers at the University of Miami School of Medicine plan to use a five-year, $2.5 million grant from the National Institute of Dental and Craniofacial Research to discover DNA variants that may function as biomarkers for susceptibility and therapeutic response fo

NEW YORK (GenomeWeb News) – The National Institute of Arthritis and Musculoskeletal and Skin Diseases plans to fund research that will use data from genome-wide association studies to discover genes and variants that influence the risk for certain diseases, according to a new funding announcement

Researchers from the Wellcome Trust Sanger Institute and elsewhere reported online in the American Journal of Human Genetics yesterday that they have tracked down a new risk gene for osteoarthritis.

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The UK has given emergency authorization for Pfizer and BioNTech's SARS-CoV-2 vaccine, the Associated Press reports.

A US advisory committee says healthcare workers and nursing home residents should be prioritized to receive a SARS-CoV-2 vaccine, according to the Financial Times.

The Wall Street Journal reports North Korean hackers have targeted half a dozen companies developing SARS-CoV-2 vaccines.

In Cell this week: long-term SARS-CoV-2 shedding, examination of the effects of a coronavirus spike protein mutation, and more.