osteoarthritis Genome-Wide Analysis More Than Doubles Loci Linked to Osteoarthritis Risk A number of the genes implicated are also the targets of approved therapeutics or of ones under testing. Osteoarthritis Risk Linked to Novel Genetic Loci The researchers noted ties between osteoarthritis-linked variants and height, and found one risk loci that implicated the Hedgehog signaling pathway. Osteoarthritis Risk Linked to Nine Novel Loci by Sanger Institute-Led Team The researchers also found that genes located near these loci were differentially expressed in healthy versus diseased cartilage. Icelandic DNA Sequences Lead to Rare Osteoarthritis Risk Variants Using extensive genetic data from an Icelandic population, researchers identified two rare variants associated with osteoarthritis and related hip replacements. Interleukin, NYU to Commercialize IL-1 Genetic Test for Osteoarthritis Progression The agreement is based on a jointly owned US patent application that claims methods of assessing a person's risk for generalized osteoarthritis based on IL-1 genotypes. Jan 24, 2013 NIAMS to Fund Research Cores for Musculoskeletal Conditions Sep 7, 2012 Miami's Hussman Institute Lands $2.5M for Persistent Pain Biomarker Hunt Jul 11, 2012 NIAMS to Fund Studies of Genes, Variants that Influence Disease Risk Aug 26, 2011 International Group Uses 1000 Genomes-Based Imputation to ID Osteoarthritis Risk Locus Feb 10, 2010 Novartis Eyeing US Market for Prexige Launch with Companion Test Premium Feb 4, 2010 Novartis Adds Companion Dx to Lumiracoxib Resubmission in Europe Oct 27, 2009 Eli Lilly Will Use GeneNews' Osteoarthritis Biomarker Technology Feb 4, 2009 Navigenics Launches Cheaper Annual Genomic Service; Will Doctors Bite? Premium Breaking News Lunaphore Technologies, University of Bern Partner on Colorectal Cancer Study People in the News: New Appointments at Biocept, Novacyt, Centogene, Illumina, More In Brief This Week: Sophia Genetics, Twist Bioscience, Dante Labs, MGI, Codex DNA, More New Products Posted to GenomeWeb: SpeeDx, Bio-Techne, NuProbe, More DiaSorin Q2 Revenues Rise 20 Percent on SARS-CoV-2 Testing Demand Cepheid Gets $28M From BARDA for SARS-CoV-2 Tests The Scan Interfering With Invasive Mussels The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels. Participation Analysis A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports. Right Whales' Decline A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC. Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.