osteoarthritis

A number of the genes implicated are also the targets of approved therapeutics or of ones under testing.

This Week in Nature

In Nature this week: genomic and other analyses suggest the plant used to make chocolate was domesticated earlier and in a different region than previously thought, and more.

The researchers noted ties between osteoarthritis-linked variants and height, and found one risk loci that implicated the Hedgehog signaling pathway.

The researchers also found that genes located near these loci were differentially expressed in healthy versus diseased cartilage.

Using extensive genetic data from an Icelandic population, researchers identified two rare variants associated with osteoarthritis and related hip replacements.

The agreement is based on a jointly owned US patent application that claims methods of assessing a person's risk for generalized osteoarthritis based on IL-1 genotypes.

NEW YORK (GenomeWeb News) – The National Institute of Arthritis and Musculoskeletal and Skin Diseases plans to use up to $2.4 million next year to fund the creation of several core centers that will support scientists studying the underlying biology of muscle and bones and the range of disorders

NEW YORK (GenomeWeb News) – Researchers at the University of Miami School of Medicine plan to use a five-year, $2.5 million grant from the National Institute of Dental and Craniofacial Research to discover DNA variants that may function as biomarkers for susceptibility and therapeutic response fo

NEW YORK (GenomeWeb News) – The National Institute of Arthritis and Musculoskeletal and Skin Diseases plans to fund research that will use data from genome-wide association studies to discover genes and variants that influence the risk for certain diseases, according to a new funding announcement

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John Mendelsohn, a former president of the University of Texas MD Anderson Cancer Center, has died, the New York Times reports.

Chinese state news agency Xinhua reports that a preliminary investigation has found He Jiankui performed his gene-editing work illegally.

Identical twins receive different estimates of ancestry from the same direct-to-consumer genetic testing firms, CBC reports.

In PNAS this week: chromosomal features of maize, adaptations in the vinous-throated parrotbill, and more.