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University of Manchester, Sano Genetics to Research Eye Diseases

The partners plan to build a database of genomic and patient-reported data to identify how genetics can impact disease outcome.

Avellino Labs Gets CLIA Certification

With the certification, the Silicon Valley-based company aims to roll out its AvaGen test for keratoconus and corneal dystrophies beginning this quarter.

Editas, Allergan Ink $90M CRISPR-Based Eye Drug Deal

Allergan will have the exclusive rights to license certain of Editas' CRISPR genome editing-based treatments for eye diseases.

Scientists Exploit SNP to Create New CRISPR/Cas9 Editing Site in Corneal Dystrophy Gene

They successfully edited the gene in mice in vivo and their approach could also work for a range of heterozygous disease-causing SNPs.

Gene Panel Outperforms Exome Sequencing for Diagnosing Inherited Eye Disorders
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Exome sequencing poorly covers some known disease genes, but identifies novel genes that that Harvard team thinks will help improve panel's diagnostic rate.

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Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.