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obesity

The Pudgy Lab

Researchers link obesity in Labrador retrievers to a deletion in their POMC gene.

In Nature this week: analysis of nuclear DNA from ancient hominin, epigenetic influence on obesity, and more.

In Cell this week: characterization of functional genomic features in breast cancer cell lines, epigenetic pattern linked to obesity, and more.

Researchers demonstrated the feasibility of doing a transcriptome-wide association study using GWAS data and imputed expression clues from reference individuals.

A genome-wide association study of some 89,000 people linked variants in circadian rhythm genes to being a morning person.

The researchers found that epigenetic marks altered the way weight control-related genes acted in genetically identical mice and in human twin pairs.

Researchers found that children who have taken macrolide antibiotics have distinctive microbiomes and that some of those changes are persistent.

Genomic and other data may soon guide personalized weight management, according to a National Institutes of Health working group report.

The grant funding is being awarded to researchers from the Geisinger Health System, Penn State University, and the University of Pennsylvania.

In PLOS this week: parent-of-origin effects, framework to uncover clinically important mutations from whole genome sequence data, and more.

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Researchers have sequenced the genome of the depth-dwelling giant squid.

Prosecutors have charged a former Drexel University professor with theft for allegedly spending federal grant money on adult entertainment and other unrelated expenses, according to the Philadelphia Inquirer.

 

Chris Collins, a former US representative, has been sentenced to more than two years in prison in an insider trading case involving an Australian biotechnology firm, the New York Times reports.

In PNAS this week: Trypanosoma brucei transcripts, estimate of people at risk of inherited retinal disease, and more.