Researchers detected a truncating mutation in the carboxypeptidase E gene in members of a Sudanese family affected by extreme obesity, glucose metabolism problems, and other symptoms.
The researchers published a proof of principle in Nature Communications of a panel designed to look at epigenetic variation in adipose tissue and are using it to study obesity and metabolic syndromes.
Women whose 21-SNP panel result indicated they were at high risk of obesity were less likely to respond to exercise by losing weight or body fat.
Through unbiased and targeted metabolite testing on urine samples from thousands of individuals in the US and the UK, researchers have narrowed in on urine compounds that coincide with body mass index.
Through their meta-analyses, consortium researchers found roles for a number of pathways in obesity risk and highlighted the varied effects of loci on men and women.
A University of Washington-led team looked at strain diversity in human gut microbiomes using a newly developed computational pipeline.
An analysis in the Proceedings of the National Academy of Sciences suggests the association between obesity and an FTO gene variant became increasingly significant in the past several decades.
With this support, Newtopia hopes to grow its business focused on urging employees to make lifestyle changes based on genetic testing and coaching.
NEW YORK (GenomeWeb) – In Nature Genetics, the University of Washington's Evan Eichler and colleagues from the US and Italy explored molecular mechanisms that can cause the genetic instability
NEW YORK (GenomeWeb) – The University of Nebraska-Lincoln has received an $11.3 million grant from the National Institutes of Health to establish a research center focused on obesity.
Microsoft co-founder Paul Allen also contributed to brain research, NPR reports.
The New York Times reports on the shifting interpretations of what some genetic variants mean over time.
In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.
MIT's Technology Review reports on Genentech's pursuit of personalized cancer vaccines.