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obesity

Rhythm is using WuXi's artificial intelligence capabilities to support drug development targeting pathways associated with genetic obesity syndromes.

Two papers in Nature Genetics found that loss-of-function variants in ADCY3 were associated with severe obesity, and that ADCY3 could be a treatment target.

University of Exeter researchers used UK Biobank data to examine the interaction of genetic risk factors for obesity, physical activity, and sleep.

In PNAS this week: host contributors to typhoid fever risk, effects of obesity-related variants near TMEM18, and more.

Lessen the Chances

Even with a genetic predisposition toward obesity, the Washington Post notes there are steps people can take to lessen that risk.

The Irish Times looks into whether everyone benefits the same from advice to exercise and eat right.

Keep on Moving

Researchers find that physical activity can attenuate the effect of genetic obesity risk, as ABC News reports.

In PLOS this week: loci linked to body mass index measurements, long non-coding RNA expression and urothelial carcinoma prognosis, and more.

An NHGRI-led team found a variant in the SEMA4D gene that was present in people of African descent, but not in people of Asian or European ancestry.

GUSTO study researchers said maternal lifestyle, fetal genetic, and fetal epigenetic factors affect birth weight and early childhood adiposity.

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The Washington Post reports on researchers' efforts to determine the effect of an increasingly common SARS-CoV-2 mutation.

Florida Politics reports Florida's law barring life, long-term care, and disability insurers from using genetic information in coverage decisions went into effect at the beginning of July.

A new analysis finds a link between popular media coverage of a scientific study and how often that paper is cited.

In Nature this week: CRISPR approaches to editing plant genomes, way to speed up DNA-PAINT, and more.