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obesity

Researchers found methylation mediators of obesity and other metabolic features by profiling individuals born after a famine called the Dutch Hunger Winter.

In Genome Biology this week: gene expression patterns in mice with obesity-linked gut microbiomes, epigenetics of identical twins, and more.

In Nature this week: a genomics search engine, and more.

In an observational study, a Tulane University-led team found that people at genetic risk of obesity who started to eat a healthy diet lost more weight than those not at risk.

Rhythm is using WuXi's artificial intelligence capabilities to support drug development targeting pathways associated with genetic obesity syndromes.

Two papers in Nature Genetics found that loss-of-function variants in ADCY3 were associated with severe obesity, and that ADCY3 could be a treatment target.

University of Exeter researchers used UK Biobank data to examine the interaction of genetic risk factors for obesity, physical activity, and sleep.

In PNAS this week: host contributors to typhoid fever risk, effects of obesity-related variants near TMEM18, and more.

Lessen the Chances

Even with a genetic predisposition toward obesity, the Washington Post notes there are steps people can take to lessen that risk.

The Irish Times looks into whether everyone benefits the same from advice to exercise and eat right.

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Kelvin Droegemeier, the director of the White House Office of Science and Technology Policy, is the new acting director of the US National Science Foundation.

An opinion piece at the Guardian discusses the state of SARS-CoV-2 testing in the UK.

Wired reports the University of California, Berkeley's Innovative Genomics Institute has transformed itself into a diagnostic lab to run SARS-CoV-2 tests.

In Nature this week: direct-capture Perturb-seq approach for combinatorial single-cell CRISPR screens, potential uses of genome-editing in breeding crops, and more.