obesity

Bloomberg reports that researchers and drug companies are modeling anti-obesity treatments after the rare genetic condition essential fructosuria.

A deep RNA sequencing analysis of adipose tissue from lean and obese individuals highlighted new and previously annotated human long intergenic noncoding RNAs.

The researchers said that examining the FGF21 allele could cast light on potential adverse and beneficial effects of therapies that target the gene.

Researchers found methylation mediators of obesity and other metabolic features by profiling individuals born after a famine called the Dutch Hunger Winter.

In Genome Biology this week: gene expression patterns in mice with obesity-linked gut microbiomes, epigenetics of identical twins, and more.

This Week in Nature

In Nature this week: a genomics search engine, and more.

In an observational study, a Tulane University-led team found that people at genetic risk of obesity who started to eat a healthy diet lost more weight than those not at risk.

Rhythm is using WuXi's artificial intelligence capabilities to support drug development targeting pathways associated with genetic obesity syndromes.

Two papers in Nature Genetics found that loss-of-function variants in ADCY3 were associated with severe obesity, and that ADCY3 could be a treatment target.

University of Exeter researchers used UK Biobank data to examine the interaction of genetic risk factors for obesity, physical activity, and sleep.

Pages

The UK's Human Fertility and Embryology Authority calls for consumer genetic testing companies to warn customers that testing could uncover family secrets, according to the Guardian.

The New York Times reports that United Nations delegates have been discussing how to govern the genetic resources of the deep sea.

Researchers have transplanted edited cells into mice that appear to combat cocaine addiction, New Scientist reports.

In PNAS this week: analysis of proteolytic enzymes secreted by circulating tumor cells, phylogenetic study of Fv1 evolution, and more.