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obesity

Northern and southern Italians further developed what appear to be genetic adaptations affecting susceptibility to obesity and melanoma, respectively.

In animal models, loss of ALK was associated with protection from obesity, even when the animals were on a high-fat diet.

Researchers saw a shift toward lower gut bifidobacterial levels and a dip in pro-inflammatory Th17 immune cells due to ketone bodies production.

In Cell this week: strategy for prophylactic antiviral CRISPR in human cells; influence of obesity, genetics, and hormone signaling on pancreatic ductal adenocarcinoma; and more.

An analysis of biobank data from Japan, the UK, and Finland found the link between obesity and lifespan was stronger among individuals with European ancestry.

In PLOS this week: signs of selection on microRNA targets, HPV sequences as markers of cervical cancer, and more.

Some of these shared loci were associated with higher BMI, but some were linked to lower BMI, particularly those also linked to schizophrenia.

In a large group of participants followed for decades, baseline body mass index outperformed a SNP-based obesity risk score for predicting midlife weight.

Just Another Diet

Washington Post columnist writes that she is skeptical about DNA-based diets.

In Science this week: sequencing study of 523 ancient individuals from South and Central Asia, and more.

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A tissue sample from the 1960s harbors a near-complete sample of HIV, IFLScience reports.

The Food and Drug Administration's decision to halt a SARS-CoV-2 study has drawn criticism, according to Stat News.

In Genome Biology this week: features affecting gut microbiome and parasite patterns, cellular interactions in lung tumor microenvironment, and more.

New analyses indicate female researchers are publishing less during the coronavirus pandemic than male researchers, according to Nature News.