Some of these shared loci were associated with higher BMI, but some were linked to lower BMI, particularly those also linked to schizophrenia.
In a large group of participants followed for decades, baseline body mass index outperformed a SNP-based obesity risk score for predicting midlife weight.
A Washington Post columnist writes that she is skeptical about DNA-based diets.
In Science this week: sequencing study of 523 ancient individuals from South and Central Asia, and more.
Different biological processes appear to drive body mass index during infancy and later in childhood and adulthood, which could inform obesity prevention strategies.
A gene-environment study involving more than 18,000 individuals suggests jogging and other forms of exercise may modify the genetic risk for obesity.
Rhythm has a drug called setmelanotide in Phase III development for genetic obesity disorders associated with variants within the melanocortin-4 pathway.
The researchers found that while BMI broadly increased over time in their Norwegian cohort, genetically predisposed individuals were more highly affected.
The firm, Phenomix Sciences, anticipates that its test will help drive adoption of medications for obesity at a time when patients are reluctant to take them.
Researchers question the value of a predictive genetic test for obesity, NPR reports.
The Los Angeles Times reports that a case of the novel coronavirus making people ill in China has been reported in the US.
A bipartisan group of senators has introduced a bill seeking increased funding for certain fields, including synthetic biology, ScienceInsider reports.
Discover magazine writes that paleoproteomics is increasing being used in archaeology, paleoanthropology, and paleontology, including a recent study of a 6,000-year-old ring.
In Nucleic Acids Research this week: mutagenic effects of ultraviolet "A" light, post-transcription effects of synonymous mutations, and more.