A deep RNA sequencing analysis of adipose tissue from lean and obese individuals highlighted new and previously annotated human long intergenic noncoding RNAs.
The researchers said that examining the FGF21 allele could cast light on potential adverse and beneficial effects of therapies that target the gene.
Researchers found methylation mediators of obesity and other metabolic features by profiling individuals born after a famine called the Dutch Hunger Winter.
In Genome Biology this week: gene expression patterns in mice with obesity-linked gut microbiomes, epigenetics of identical twins, and more.
In Nature this week: a genomics search engine, and more.
In an observational study, a Tulane University-led team found that people at genetic risk of obesity who started to eat a healthy diet lost more weight than those not at risk.
Rhythm is using WuXi's artificial intelligence capabilities to support drug development targeting pathways associated with genetic obesity syndromes.
Two papers in Nature Genetics found that loss-of-function variants in ADCY3 were associated with severe obesity, and that ADCY3 could be a treatment target.
University of Exeter researchers used UK Biobank data to examine the interaction of genetic risk factors for obesity, physical activity, and sleep.
In PNAS this week: host contributors to typhoid fever risk, effects of obesity-related variants near TMEM18, and more.
In a commentary at eLife, Brandeis University's Eve Marder calls on researchers to value and pursue truth.
Researchers have developed a way to quickly edit white blood cells, according to the New York Times.
In Science this week: rice gene enables plants to grow quickly in times of flooding, and more.
Education-linked genetic variants could also predict a small portion of a person's social mobility, Newsweek reports.