obesity

A Regeneron-led team identified four variants that affect LDL cholesterol levels and are much more prevalent among Southwestern American Indians.

Researchers found that diurnal gut microbe fluctuations are disrupted in individuals with type 2 diabetes, leading to a bacterial signature for risk profiling.

Northern and southern Italians further developed what appear to be genetic adaptations affecting susceptibility to obesity and melanoma, respectively.

In animal models, loss of ALK was associated with protection from obesity, even when the animals were on a high-fat diet.

Researchers saw a shift toward lower gut bifidobacterial levels and a dip in pro-inflammatory Th17 immune cells due to ketone bodies production.

An analysis of biobank data from Japan, the UK, and Finland found the link between obesity and lifespan was stronger among individuals with European ancestry.