The results, presented at the AACR meeting, also included data from a subset of 50 patients who have so far been tested using Natera's multiplex PCR technology.

The results support potential future interchangeability of these assays to guide therapy with different immune checkpoint inhibitors.

Inivata has completed the analytical validation of its 35-gene ctDNA test and plans to conduct clinical validation studies from labs in North Carolina and the UK.

By showing flexibility and requiring a CDx in the post-market setting, the agency hopes to encourage the development of a universal NGS test.

The partners will study testing rates, repeat biopsies and their complications, and other factors that preclude routine genotyping in NSCLC.

National Government Services' coverage criteria are different from criteria proposed by Palmetto last year, which may impact companies like Foundation Medicine.

The companies have launched a study measuring the clinical and cost benefits of using Foundation Medicine's FoundationOne genomic profiling assay. 

Both companies are using their assays to detect genetic alterations that confer a higher chance of response to the drug in a newly-announced Phase 2 trial.

Younger NSLCL patients may benefit more from broad genomic profiling because they are more likely to have one of several targetable mutations.

The new study will evaluate how different assays measuring PD-L1 expression compare to one another, an issue raised in recently published research.



Chinese state news agency Xinhua reports that a preliminary investigation has found He Jiankui performed his gene-editing work illegally.

John Mendelsohn, a former president of the University of Texas MD Anderson Cancer Center, has died, the New York Times reports.

Identical twins receive different estimates of ancestry from the same direct-to-consumer genetic testing firms, CBC reports.

In PNAS this week: chromosomal features of maize, adaptations in the vinous-throated parrotbill, and more.