neurological disorders DNA Methylation Differences in Amyotrophic Lateral Sclerosis Point to Risk Pathways An epigenome-wide association meta-analysis highlighted 45 differentially methylated positions in ALS patient blood samples, offering insights into related pathways and traits. Migraine GWAS Points to Subtype-Specific Loci, Potential Mechanisms Researchers linked migraine risk to 123 loci, including risk variants not found in the past and loci implicated in migraine subtypes. Brain Vascular Malformation Insights Gleaned From Single-Cell Atlas With single-cell RNA sequencing, researchers characterized expression and cell type shifts in brain vascular samples from individuals with or without brain arteriovenous malformations. GATC Health, Liquid Biosciences Partner to Provide Multiomic Biomarker Discovery The two California firms are linking their bioinformatics platforms in hopes of accelerating biomarker and drug discovery processes for pharma companies. With $50M in New Funding, Congenica Works on Platform Upgrades for Clinical Applications Premium With its recent $50 million VC round, the British bioinformatics firm is targeting growth in new applications as it accelerates tertiary data analysis. Jul 8, 2020 Twist Bioscience, Takeda Pharma Partner to Develop Antibodies for Oncology, Rare Diseases May 20, 2020 TruGenomix, BlueBee Partner on Biomarker Development for PTSD Risk Assessment Jan 23, 2020 Autism Sequencing Study Uncovers New Disease-Associated Genes, Functional Clues Jan 8, 2020 RNA-Seq in Blood Cell Line Enables Molecular Diagnosis of Neurodevelopmental Disorders Premium Dec 27, 2019 SPARK Autism Research Initiative Obtains First Results, Explores New Recruitment Strategies Premium Jul 11, 2019 Microsoft, Seattle Children's Seek Genetic Markers for SIDS Through Whole-Genome Sequencing Premium Jun 13, 2019 GlaxoSmithKline, UC's Doudna Establish $67M Genomics, CRISPR Research Lab Mar 7, 2019 NYCKidSeq Project Aims to Improve Communication of Genomic Test Results Premium Nov 30, 2018 Repeat Expansion Disease Detection From Short Reads Shows Potential for Clinical Use Premium Oct 11, 2018 Undiagnosed Diseases Network Reports Diagnostic Rates, Impact on Treatment Sep 26, 2018 GWAS Reveals Common, Polygenic Contributors to Neurodevelopmental Disorders Jun 13, 2018 Invitae Study Reveals CNV Contributions to Pathogenic Variation in Mendelian Disease Genes May 22, 2018 Cytox, Mayo Clinic Team Up to Study Alzheimer's Disease Assays Mar 6, 2018 Synesthesia Family Exomes Lead to Rare Axon-Related Gene Variants Feb 9, 2018 Q-State Subsidiary Buys Claritas Assets, Plans Relaunch of Lab to Support Drug Discovery Programs Premium Jan 12, 2018 GeneDx, Radboud UMC Collaborate on Research Into Neurodevelopmental Disorders Nov 22, 2017 MNG Laboratories Combines Molecular, Metabolic Testing to Help Improve Diagnosis of Rare Disorders Premium Sep 14, 2017 PerkinElmer to Collaborate With In-Depth Genomics on WGS-Based Diagnostic Program Jun 21, 2017 Tourette Syndrome Risk Tied to Rare CNVs in Two Genes Mar 3, 2017 Abbott in Collaborations to Develop Biomarker Test for Traumatic Brain Injury Load More Breaking News People in the News at Pacific Biosciences, Metabolon, NeoGenomics, More New Products Posted to GenomeWeb: Tethis, Invitae, PerkinElmer, More In Brief This Week: Thermo Fisher Scientific, Bruker, Quantum-Si, BioMérieux, More Luminex Obtains CE Marking for MDx Panel to Detect Flu A/B, RSV, COVID-19 Palmetto Finalizes Positive LCD for Prostate Cancer Risk Tests Gene Expression, Histology Reveal Clues for Targeted Rheumatoid Arthritis Treatment The Scan Call for a Different Tack Experts weigh the value of recent experiments testing genetically modified pig kidneys using brain-dead individuals, according to Nature News. Wastewater Warning The New York Times reports that wastewater surveillance in some parts of the US point to a possible surge. Can't Get in the Program Due to the Northern Ireland protocol dispute, the European Union is preventing UK researchers from joining the Horizon Europe research program, the Times of London reports. Science Paper on Spatial-Controlled Genome Editing In Science this week: approach to enable a CRISPR-Cas13a-based system to be used as a cancer therapy.