neurodegenerative disease
Transcriptomic Data May Provide New Way to Classify, Compare Brain Disorders
The researchers studied gene expression of disease-related genes among neurotypical brains and found associations that were previously unknown.
Schizophrenia Risk Genes Coexpressed Differently Across Lifetime, Brain Regions
RNA sequencing of 833 post-mortem brain samples revealed changes in coexpression patterns and novel gene associations involved in the development of schizophrenia.
APOE Missense Variant Linked to Increased Alzheimer's Disease Risk in African Americans
A case-control study found that the APOE ε3[R145C] variant, seen in 4 percent of African Americans, increases AD risk in individuals with the ε3/ε4 genotype.
Late-Onset Ataxia Linked to New Repeat Expansion in FGF14 Gene
The repeat expansion appears to coincide with late-onset cerebellar ataxia risk, particularly in patients from a French-Canadian population.
Centogene to Offer Genomic Data for Rare Neurodegenerative Diseases on BC Platforms Network
The partnership will expand genomics data on the BCRquest research network by 20 percent and diversify BC Platforms' research dataset.