neuroblastoma Single-Cell Transcriptomic Analysis Traces Neuroblastomas to Developing Adrenal Neuroblasts The analysis further found that low-risk tumors might develop from cells further along in development, while high-risk ones might develop from earlier-stage cells. Childhood Cancer Study Reveals Pan-Neuroblastoma Cell State The researchers said this unexpected homogeneity in the cellular identity of neuroblastoma could lead to the development of targeted treatments. Neuroblastoma Super Enhancer Profiles Pinpoint Four Epigenetic Subtypes Using a combination of genomic and epigenomic profiling, researchers spelled out super enhancer-based subtypes, including one linked to poor clinical outcomes. Adrenal Neuroblastoma Cell Features Found by Single-Cell Transcriptome Sequencing Single-cell RNA sequencing on adrenal gland samples with or without neuroblastoma helped track down key malignant subtypes and tumor features, providing prognostic clues. Human Tumor Atlas Network Team Shares Strategy for Tracking Tumor Transitions A new paper outlines an upcoming effort to trace tumor development and trajectory in time and space using single-cell genetics and other genomic methods. Dec 16, 2019 Neuroblastoma Study Reveals Rearrangements Originating From Extrachromosomal Circular DNA Jul 23, 2019 Pediatric Oncologists Employing Variety of Sequencing Strategies for Treatment, Research Premium Jun 18, 2019 Next-Generation Sequencing of Pediatric Cancer Patients Could Transform Treatment Paradigms Premium Dec 6, 2018 Neuroblastoma Molecular Analysis Leads to Potential Prognostic Markers Jan 12, 2018 Molecular Analysis Offers Treatment Hints for Rare Nasal Cavity Cancer Dec 30, 2015 Researchers Model JNK Signaling to Predict Survival in Neuroblastoma Premium Aug 5, 2015 UCSC Pediatric Cancer Project to Use Pan-Cancer Analysis Approach to Match Patients to Treatment Premium Jun 29, 2015 Sequencing Study Sees Frequent RAS-MAPK Mutations at Neuroblastoma Relapse Feb 17, 2015 With Latest Orphan Status for Entrectinib in CRC, Ignyta Continues to Pursue Precision Rx Approach Premium Nov 12, 2014 Study Teases Out Truly Drug-sensitive ALK Mutations ahead of Neuroblastoma Phase III Trial Premium May 5, 2014 NYGC, Sohn Conference Foundation Launch Pediatric Cancer Research Center Mar 19, 2014 European Study Suggests mRNA Signature Could Be Useful Prognostic in Neuroblastoma Premium Dec 3, 2012 CHOP, Johns Hopkins-led Team Finds Changes to Chromatin-Related Genes in Aggressive Neuroblastomas Mar 14, 2012 PCGP Researchers Find Gene Tied To Neuroblastoma Age-at-Diagnosis Nov 10, 2011 Dell Supports TGen's Pediatric Cancer Project with Cloud Jun 1, 2011 Van Andel Receives FDA OK to Test Feasibility of Genomically Guided Pediatric Cancer Treatment Premium Apr 6, 2011 At AACR, Findings from Broad-Led Effort to Sequence Neuroblastoma Exomes Mar 26, 2009 Genomics vs. Cancer Premium Breaking News Myasthenia Gravis Study Identifies Genetic Risk Loci Affecting Acetylcholine Receptor Mammoth Biosciences High-Throughput CRISPR-Based COVID Test Gets FDA EUA Illumina, National Cancer Center Japan Collaborate on Nasopharyngeal Cancer Study Fluidigm Obtains $250M Investment, Changing Name to Standard BioTools SeqOne Genomics Closes €20M Series A Financing NeoGenomics Partners With Biomarker Collaborative to Provide Lung Cancer Resources The Scan For STEM Students to Stay New policy changes will make it easier for international STEM students to stay in the US after graduation, the Wall Street Journal reports. To Inform or Not, To Know or Not The New York Times writes that some genetic biobanks may re-contact donors if they spot something troublesome, but it notes that not all donors want that information. Rapid Test Studies Researchers are examining why rapid tests may be less effective at detecting the Omicron variant and how to improve them, NPR says. PLOS Papers on SARS-CoV-2 Diversity in Delaware, Metastatic Breast Cancer, Adiposity GWAS In PLOS this week: genomic analysis of SARS-CoV-2 isolates from Delaware, gene expression and protein-protein interaction patterns in metastatic breast cancer, and more.