neuroblastoma
Single-Cell Transcriptomic Analysis Traces Neuroblastomas to Developing Adrenal Neuroblasts
The analysis further found that low-risk tumors might develop from cells further along in development, while high-risk ones might develop from earlier-stage cells.
Childhood Cancer Study Reveals Pan-Neuroblastoma Cell State
The researchers said this unexpected homogeneity in the cellular identity of neuroblastoma could lead to the development of targeted treatments.
Neuroblastoma Super Enhancer Profiles Pinpoint Four Epigenetic Subtypes
Using a combination of genomic and epigenomic profiling, researchers spelled out super enhancer-based subtypes, including one linked to poor clinical outcomes.
Adrenal Neuroblastoma Cell Features Found by Single-Cell Transcriptome Sequencing
Single-cell RNA sequencing on adrenal gland samples with or without neuroblastoma helped track down key malignant subtypes and tumor features, providing prognostic clues.
Human Tumor Atlas Network Team Shares Strategy for Tracking Tumor Transitions
A new paper outlines an upcoming effort to trace tumor development and trajectory in time and space using single-cell genetics and other genomic methods.