neuroblastoma Single-Cell Transcriptomic Analysis Traces Neuroblastomas to Developing Adrenal Neuroblasts The analysis further found that low-risk tumors might develop from cells further along in development, while high-risk ones might develop from earlier-stage cells. Childhood Cancer Study Reveals Pan-Neuroblastoma Cell State The researchers said this unexpected homogeneity in the cellular identity of neuroblastoma could lead to the development of targeted treatments. Neuroblastoma Super Enhancer Profiles Pinpoint Four Epigenetic Subtypes Using a combination of genomic and epigenomic profiling, researchers spelled out super enhancer-based subtypes, including one linked to poor clinical outcomes. Adrenal Neuroblastoma Cell Features Found by Single-Cell Transcriptome Sequencing Single-cell RNA sequencing on adrenal gland samples with or without neuroblastoma helped track down key malignant subtypes and tumor features, providing prognostic clues. Human Tumor Atlas Network Team Shares Strategy for Tracking Tumor Transitions A new paper outlines an upcoming effort to trace tumor development and trajectory in time and space using single-cell genetics and other genomic methods. Dec 16, 2019 Neuroblastoma Study Reveals Rearrangements Originating From Extrachromosomal Circular DNA Jul 23, 2019 Pediatric Oncologists Employing Variety of Sequencing Strategies for Treatment, Research Premium Jun 18, 2019 Next-Generation Sequencing of Pediatric Cancer Patients Could Transform Treatment Paradigms Premium Dec 6, 2018 Neuroblastoma Molecular Analysis Leads to Potential Prognostic Markers Jan 12, 2018 Molecular Analysis Offers Treatment Hints for Rare Nasal Cavity Cancer Dec 30, 2015 Researchers Model JNK Signaling to Predict Survival in Neuroblastoma Premium Aug 5, 2015 UCSC Pediatric Cancer Project to Use Pan-Cancer Analysis Approach to Match Patients to Treatment Premium Jun 29, 2015 Sequencing Study Sees Frequent RAS-MAPK Mutations at Neuroblastoma Relapse Feb 17, 2015 With Latest Orphan Status for Entrectinib in CRC, Ignyta Continues to Pursue Precision Rx Approach Premium Nov 12, 2014 Study Teases Out Truly Drug-sensitive ALK Mutations ahead of Neuroblastoma Phase III Trial Premium May 5, 2014 NYGC, Sohn Conference Foundation Launch Pediatric Cancer Research Center Mar 19, 2014 European Study Suggests mRNA Signature Could Be Useful Prognostic in Neuroblastoma Premium Dec 3, 2012 CHOP, Johns Hopkins-led Team Finds Changes to Chromatin-Related Genes in Aggressive Neuroblastomas Mar 14, 2012 PCGP Researchers Find Gene Tied To Neuroblastoma Age-at-Diagnosis Nov 10, 2011 Dell Supports TGen's Pediatric Cancer Project with Cloud Jun 1, 2011 Van Andel Receives FDA OK to Test Feasibility of Genomically Guided Pediatric Cancer Treatment Premium Apr 6, 2011 At AACR, Findings from Broad-Led Effort to Sequence Neuroblastoma Exomes Mar 26, 2009 Genomics vs. Cancer Premium Breaking News Pediatric Medulloblastoma Subgroups May Benefit from Lower-Dose Radiation Therapy Space Radiation Shows Limited Effects on Mammalian Sperm DNA, Fertility Bluestar Genomics Sues Former Consultant, Ludwig Institute for Cancer Research Over IP Ownership New Products Posted to GenomeWeb: 10x Genomics, Swift Biosciences, Agilent Technologies, More In Brief This Week: Quantum-Si, TGen, Yale, and More People in the News: New Appointments at Invitae, PGDx, Oxford Nanopore, PacBio, More The Scan Fertility Fraud Found Consumer genetic testing has uncovered cases of fertility fraud that are leading to lawsuits, according to USA Today. Ties Between Vigorous Exercise, ALS in Genetically At-Risk People Regular strenuous exercise could contribute to motor neuron disease development among those already at genetic risk, Sky News reports. Test Warning The Guardian writes that the US regulators have warned against using a rapid COVID-19 test that is a key part of mass testing in the UK. Science Papers Examine Feedback Mechanism Affecting Xist, Continuous Health Monitoring for Precision Medicine In Science this week: analysis of cis confinement of the X-inactive specific transcript, and more.