myocardial infarction Complex Genetics Identified for Heart Condition Affecting Seemingly Healthy Young Women A spontaneous coronary condition that is overrepresented in young women had a polygenic risk score linked to lower-than-usual atherosclerosis-related heart disease risk. Genetic Study Explains Link Between Osteoporosis Drug, Cardiovascular Risk The findings underscore the value of carrying out large-scale human genetic analyses as part of drug target identification and validation efforts. Coronary Heart Disease Polygenic Risk Scores Differ in Utility Between Ethnic Groups Researchers investigated how well four polygenic risk scores for coronary heart disease performed in three racial or ethnic groups in the US. Fauna Bio Awarded $229K NIH Grant for Animal Genomics-Based Drug Discovery Platform The company aims to repurpose drugs by translating the mechanisms that allow hibernating animals to withstand the stresses of extended sleep. Genetic Testing Can Guide Medication Decisions After Heart Procedure, Study Finds A European study, published today in NEJM, used a POC, PCR-based system to perform CYP2C19 genotyping to guide platelet inhibitor therapy. Aug 17, 2017 Heart Disease Risk Alleles Reported In 17th Century Korean Mummy Jul 25, 2017 Genetic Predisposition to High Blood Calcium Linked to Increased Heart Disease Risk Dec 1, 2016 Therapies Targeting PCSK9 Would Reduce Cardiovascular, Increase Diabetes Risk Dec 29, 2014 Q&A: Estonian Genome Center's Andres Metspalu on Biobanks, Arrays, and Personalized Medicine Premium Dec 10, 2014 Exome Sequencing Leads to Rare Heart Attack Risk Variants in Two Genes Apr 9, 2014 Study Supports 'Undetectable' Troponin T Level to Rule out MI, Reduce ER Chest Pain Admissions Premium Dec 19, 2013 Allele in Stress Reaction-linked Gene Associated with Cardiovascular Events, Death Sep 5, 2013 Beth Israel Team Using RainDance Digital PCR to Measure miRNA Biomarkers in Cardiac Patients Premium Jun 28, 2013 Slow Sales Leave Some Proteomics Dx Firms Questioning Value of Large Clinical Lab Deals Premium Jun 21, 2013 Aviir Raises Final $10 Million Tranche of a $30 Million Round Mar 1, 2013 With $10M in Funding and New Distribution Pact, Aviir Rolls out Protein Test for Cardiac Risk Premium Feb 19, 2013 Partners & Partners, Aviir Ink Deal to Distribute Tests in the Middle East and North Africa Feb 13, 2013 Cardio Test Developer Aviir Raises Additional $10M Sep 14, 2012 Qiagen Inks China Point-of-Care Diagnostics Deal Aug 9, 2012 BG Medicine Q2 Revenues Spike; Company Withdraws FDA Submission for CardioScore Test Jun 18, 2012 Population Genetics, U of Oxford Collaborate on Research for Myocardial Infarction, Diabetes May 17, 2012 BG Medicine Q1 Revenues Fall but Galectin-3 Sales Jump as Company Pursues Expanded Use for Test Premium Apr 10, 2012 SomaLogic, Hunt Biosciences Search for Cardiovascular Protein Biomarkers Apr 4, 2012 PGx Highlights from American College of Cardiology Annual Meeting Premium Mar 29, 2012 Intermountain Team Reports on miRNAs as Biomarkers of Imminent Heart Attack Premium Load More Breaking News Analysis of Ancient Plaque Points to Agriculture-Related Oral Microbiome Changes in Southern Europe Gene-Disrupting Ultra-Rare Variants More Common in Children With Autism Spectrum Disorder CDC to Withdraw EUA for COVID-19 Test; FDA Revokes Three Other EUAs for Non-Use, Agency Clearance Quidel, Beckman Coulter Settle Legal Dispute Over Cardiac Immunoassay Business Top Five Articles on GenomeWeb Last Week: Pacific Biosciences, Illumina, Natera, and More Canine Genetics Firm Embark Veterinary Raises $75M in Series B Round The Scan Purnell Choppin Dies Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post. Effectiveness May Decline, Data From Israel Suggests The New York Times reports that new Israeli data suggests a decline in Pfizer-BioNTech SARS-CoV-2 vaccine effectiveness against Delta variant infection, though protection against severe disease remains high. To See Future Risk Slate looks into the use of polygenic risk scores in embryo screening. PLOS Papers on Methicillin-Resistant Staphylococcus, Bone Marrow Smear Sequencing, More In PLOS this week: genomic analysis of methicillin-resistant Staphylococcus pseudintermedius, archived bone marrow sequencing, and more.