myocardial infarction Complex Genetics Identified for Heart Condition Affecting Seemingly Healthy Young Women A spontaneous coronary condition that is overrepresented in young women had a polygenic risk score linked to lower-than-usual atherosclerosis-related heart disease risk. Genetic Study Explains Link Between Osteoporosis Drug, Cardiovascular Risk The findings underscore the value of carrying out large-scale human genetic analyses as part of drug target identification and validation efforts. Coronary Heart Disease Polygenic Risk Scores Differ in Utility Between Ethnic Groups Researchers investigated how well four polygenic risk scores for coronary heart disease performed in three racial or ethnic groups in the US. Fauna Bio Awarded $229K NIH Grant for Animal Genomics-Based Drug Discovery Platform The company aims to repurpose drugs by translating the mechanisms that allow hibernating animals to withstand the stresses of extended sleep. Genetic Testing Can Guide Medication Decisions After Heart Procedure, Study Finds A European study, published today in NEJM, used a POC, PCR-based system to perform CYP2C19 genotyping to guide platelet inhibitor therapy. Aug 17, 2017 Heart Disease Risk Alleles Reported In 17th Century Korean Mummy Jul 25, 2017 Genetic Predisposition to High Blood Calcium Linked to Increased Heart Disease Risk Dec 1, 2016 Therapies Targeting PCSK9 Would Reduce Cardiovascular, Increase Diabetes Risk Dec 29, 2014 Q&A: Estonian Genome Center's Andres Metspalu on Biobanks, Arrays, and Personalized Medicine Premium Dec 10, 2014 Exome Sequencing Leads to Rare Heart Attack Risk Variants in Two Genes Apr 9, 2014 Study Supports 'Undetectable' Troponin T Level to Rule out MI, Reduce ER Chest Pain Admissions Premium Dec 19, 2013 Allele in Stress Reaction-linked Gene Associated with Cardiovascular Events, Death Sep 5, 2013 Beth Israel Team Using RainDance Digital PCR to Measure miRNA Biomarkers in Cardiac Patients Premium Jun 28, 2013 Slow Sales Leave Some Proteomics Dx Firms Questioning Value of Large Clinical Lab Deals Premium Jun 21, 2013 Aviir Raises Final $10 Million Tranche of a $30 Million Round Mar 1, 2013 With $10M in Funding and New Distribution Pact, Aviir Rolls out Protein Test for Cardiac Risk Premium Feb 19, 2013 Partners & Partners, Aviir Ink Deal to Distribute Tests in the Middle East and North Africa Feb 13, 2013 Cardio Test Developer Aviir Raises Additional $10M Sep 14, 2012 Qiagen Inks China Point-of-Care Diagnostics Deal Aug 9, 2012 BG Medicine Q2 Revenues Spike; Company Withdraws FDA Submission for CardioScore Test Jun 18, 2012 Population Genetics, U of Oxford Collaborate on Research for Myocardial Infarction, Diabetes May 17, 2012 BG Medicine Q1 Revenues Fall but Galectin-3 Sales Jump as Company Pursues Expanded Use for Test Premium Apr 10, 2012 SomaLogic, Hunt Biosciences Search for Cardiovascular Protein Biomarkers Apr 4, 2012 PGx Highlights from American College of Cardiology Annual Meeting Premium Mar 29, 2012 Intermountain Team Reports on miRNAs as Biomarkers of Imminent Heart Attack Premium Load More Breaking News Biocartis Receives FDA 510(k) Clearance for Sepsis Assay DNA Script Receives CE Mark for Syntax Enzymatic DNA Synthesis Platform Exact Sciences, Pfizer End Cologuard Copromotion Agreement Genetron Health Q3 Revenues up 36 Percent, Firm Announces AstraZeneca MRD Partnership BioMark Diagnostics, AstraZeneca, Pfizer, Others Partner in Lung Cancer Screening Project Akoya Receives CLIA Certification for Biopharma Solutions Laboratory The Scan Looking for Omicron NPR reports that SARS-CoV-2 testing in the US has gotten better but also that some experts say more needs to be done to better track the Omicron variant. Holmes Alleges Abuse The Associated Press reports that Theranos' Elizabeth Holmes has testified at her wire fraud trial that her business and romantic partner abused her. Bit More Diverse, But More to Do While Black and Hispanic patients are more likely to participate in cancer clinical trials than previously, they are still underrepresented, according to US News & World Report. PNAS Papers on Yeast Gene Silencing, Zika Virus Inhibition, Immunoglobulin Hypermutation In PNAS this week: gene silencing in Saccharomyces cerevisiae, possible neuroprotective role for SHFL in a mouse model of Zika virus infection, and more.