myeloproliferative disease Single-Cell Analysis Elucidates Mutation Patterns in Myeloid Malignancies Researchers combined protein expression with mutational analysis to map the somatic genotype and clonal architecture of AML with its immunophenotype. Single-Cell Method Could Eliminate Need for Mouse Models to Study Cancer Treatment Resistance Premium The method allows for the annotation of cells by their genotype and capture of single-cell transcriptomes, even when the cells aren't morphologically distinct. Acute Myeloid Leukemia Analysis Brings Together Integrated Omic, Drug Response Profiles Members of the Beat AML consortium uncovered relationships between somatic mutations, gene expression profiles, and sensitivity to more than 100 drugs. Myeloproliferative Neoplasms Fall Into Genetic Subgroups With Distinct Clinical Phenotypes In combination with other clinical data, the genomic subtypes were able to predict patients' outcomes and could be used to help guide treatments. AMP Report Recommends Genes for Chronic Myeloid Neoplasm Sequencing Panels The working group reviewed data to identify a minimum of 34 commonly mutated genes that should be included in pan-myeloid targeted panels. Jan 23, 2018 Qiagen JAK2 Test Gets FDA Clearance for Additional Blood Cancer Types Mar 30, 2017 Qiagen Gets FDA Clearance for JAK2 Assay to Help Diagnose Blood Cancer Type Jun 8, 2016 DNA Sequencing Illuminates 11 Genetic Subtypes of AML Premium Apr 8, 2015 GWAS Reveals Loci Linked to Myeloproliferative Neoplasm Risk Feb 11, 2015 Mutation Order May Impact Clinical Outcome of Myeloproliferative Neoplasms Premium Nov 19, 2014 Dana-Farber, Brigham and Women's Develop NGS Panel for Rapid Diagnosis of Hematologic Cancers Premium Sep 8, 2011 Dx Focus Sep 8, 2011: Clinical and Regulatory PCR and Nucleic Acid Testing News Premium Sep 7, 2011 Qiagen, Lilly Partner to Develop JAK2 Companion Test for Investigational Blood Cancer Drug Premium Jul 19, 2011 Univ. of Cambridge Lands $6.3M for Blood Cancer Study Jun 16, 2011 Qiagen to Expand QIASymphony RGQ Test Menu with Ipsogen Buy Premium Breaking News Lunaphore Technologies, University of Bern Partner on Colorectal Cancer Study People in the News: New Appointments at Biocept, Novacyt, Centogene, Illumina, More In Brief This Week: Sophia Genetics, Twist Bioscience, Dante Labs, MGI, Codex DNA, More New Products Posted to GenomeWeb: SpeeDx, Bio-Techne, NuProbe, More DiaSorin Q2 Revenues Rise 20 Percent on SARS-CoV-2 Testing Demand Cepheid Gets $28M From BARDA for SARS-CoV-2 Tests The Scan Interfering With Invasive Mussels The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels. Participation Analysis A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports. Right Whales' Decline A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC. Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.