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myelodysplastic syndrome

Researchers sequenced samples from hundreds of individuals with aplastic anemia to narrow in on somatic mutation and clonal evolution patterns in the disease.

The 95-gene test is for detecting leukemia, myelodysplastic syndromes, and myeloproliferative disorders and can return results in less than one week.

NEW YORK (GenomeWeb) – Moffitt Cancer Center and M2Gen today said they have been awarded a seven-year, $7.3 million contract from the National Heart, Lung, and Blood Institute to coordinate a central laboratory and biorepository for research into myelodysplastic syndromes.

NEW YORK (GenomeWeb) – Cancer Genetics today announced a collaboration with Columbia University researchers to identify more accurate diagnostic and prognostic biomarkers for myelodysplastic syndromes.

NEW YORK (GenomeWeb News) – The European Union plans to fund new research seeking to establish the clinical utility of epigenetic biomarkers for blood-based diseases under its Blueprint consortium program, a €30 million ($39.8 million) effort focused on advancing hematopoietic biomarkers.

NEW YORK (GenomeWeb News) – RainDance Technologies today said that it has completed a collaboration with MLL Munich Leukemia Laboratory on the development of a panel for use in the sequence-based analysis of acute myeloid leukemia and myelodysplastic syndromes.

The researchers used next-generation sequencing, Sanger sequencing, and mass-spectrometric genotyping to examine samples from patients with myelodysplastic syndromes and found somatic mutations in 18 genes.

With the assay, the Stanford researchers have begun examining protein phosphorylation levels in a variety of cancer types. The team has also entered into collaborations with several pharmaceutical firms to investigate the effects of therapeutic agents on protein phosphorylation levels in tumor cells.

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The Wall Street Journal looks into FamilyTreeDNA's handling of genetic genealogy searches by law enforcement.

In a point-counterpoint in the Boston Globe, researchers discuss the potential of gene editing to prevent Lyme disease, but also the pitfalls of doing so.

MIT's Technology Review reports that researchers hope to develop a CRISPR-based pain therapy.

In Science this week: atlas of malaria parasites' gene expression across their life cycles, and more.