myelodysplastic syndrome Whole-Genome Sequencing Could Replace Cytogenetics in Assessing AML, Myelodysplastic Syndromes The researchers found that sequencing was accurate and could even detect chromosomal changes missed by cytogenetics at almost a similar price. Clinicians Face New Intervention Questions as Clonal Hematopoiesis Mutation Data Evolves Premium Increased incidental detection of clonal hematopoiesis and new considerations for mutations in myelodysplastic precursors herald improved precision medicine strategies. MSK Clonal Hematopoiesis Clinic Aims to Drive New Strategies for Cancer Risk Assessment, Prevention Premium The program is in its third year monitoring individuals with these mutations to try to detect disease early, understand their risk, and develop preventive treatments. Study Spells Out Immune, Genomic, Epigenomic Interactions in Hematological Malignancies Transcriptomic and multi-omic data spanning more than 10,000 samples helped map "immunogenomic" interactions that may inform treatment outcomes and targets. Mission Bio, Onconova Therapeutics Sign Cancer Therapy Research Partnership Onconova will use Mission Bio's Tapestri platform to study rigosertib — a drug that Onconova is developing — to target the RAS mutation in myelodysplastic syndromes. Aug 8, 2019 Dominant-Negative Effect Detected for Missense TP53 Mutations in Myeloid Cancers Jul 17, 2019 Cancer Drug Discovery Firm Notable Nabs $40M in Series B Funding Round Jan 3, 2019 Tumor Sequencing May Pick Up Mutations Caused by Coexistent Blood Disorder Sep 13, 2018 Myelodysplastic Syndrome Progression Informed by Post-Treatment Mutation Sequencing Aug 22, 2018 AMP Report Recommends Genes for Chronic Myeloid Neoplasm Sequencing Panels Feb 9, 2017 Myelodysplastic Syndrome Mutations Offer Prognostic Hints for Stem Cell Transplant Patients Aug 17, 2016 Cancer Genetics Receives NY State Approval for NGS-Based Cancer Panel Jun 8, 2016 DNA Sequencing Illuminates 11 Genetic Subtypes of AML Premium Jul 2, 2015 Sequencing Offers Clues to Clonal Evolution in Aplastic Anemia Nov 19, 2014 Dana-Farber, Brigham and Women's Develop NGS Panel for Rapid Diagnosis of Hematologic Cancers Premium Nov 5, 2014 NHLBI Awards $7.3M Contract to Moffitt, M2Gen to Coordinate Lab, Biorepository for MDS Study Oct 13, 2014 Cancer Genetics, Columbia Researchers Collaborate on MDS Biomarkers Sep 10, 2013 EU Blueprint Effort to Fund Epigenetic Biomarker Projects Jun 25, 2012 RainDance, MLL Collaborate on Leukemia Panel Jul 27, 2011 Sequencing/Genotyping Combination Yields Somatic Mutations with Prognostic and Dx Potential in MDS Premium Oct 15, 2010 Stanford Researchers Use Nano-Immunoassay to Study Protein Phosphoisoforms Related to Cancer Premium Breaking News Lunaphore Technologies, University of Bern Partner on Colorectal Cancer Study People in the News: New Appointments at Biocept, Novacyt, Centogene, Illumina, More In Brief This Week: Sophia Genetics, Twist Bioscience, Dante Labs, MGI, Codex DNA, More New Products Posted to GenomeWeb: SpeeDx, Bio-Techne, NuProbe, More DiaSorin Q2 Revenues Rise 20 Percent on SARS-CoV-2 Testing Demand Cepheid Gets $28M From BARDA for SARS-CoV-2 Tests The Scan Interfering With Invasive Mussels The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels. Participation Analysis A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports. Right Whales' Decline A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC. Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.