myelodysplastic syndrome

Researchers identified mutations present prior to allogeneic hematopoietic stem cell transplantation that coincided with MDS survival and relapse.

The firm said its Focus::Myeloid NGS-based panel for myeloid malignancies provides information for diagnosis, prognosis, treatment, and risk stratification of patients.

The study expands on the known genetic subtypes, shows that they are correlated with clinical outcome, and paves the way for better subtype-driven patient management. 

This Week in PNAS

In PNAS this week: decreased DOCK4 expression in myelodysplastic syndromes plus anemia, hepatitis A evolution, and more.

Researchers sequenced samples from hundreds of individuals with aplastic anemia to narrow in on somatic mutation and clonal evolution patterns in the disease.

The 95-gene test is for detecting leukemia, myelodysplastic syndromes, and myeloproliferative disorders and can return results in less than one week.

NEW YORK (GenomeWeb) – Moffitt Cancer Center and M2Gen today said they have been awarded a seven-year, $7.3 million contract from the National Heart, Lung, and Blood Institute to coordinate a central laboratory and biorepository for research into myelodysplastic syndromes.

NEW YORK (GenomeWeb) – Cancer Genetics today announced a collaboration with Columbia University researchers to identify more accurate diagnostic and prognostic biomarkers for myelodysplastic syndromes.

NEW YORK (GenomeWeb News) – The European Union plans to fund new research seeking to establish the clinical utility of epigenetic biomarkers for blood-based diseases under its Blueprint consortium program, a €30 million ($39.8 million) effort focused on advancing hematopoietic biomarkers.

NEW YORK (GenomeWeb News) – RainDance Technologies today said that it has completed a collaboration with MLL Munich Leukemia Laboratory on the development of a panel for use in the sequence-based analysis of acute myeloid leukemia and myelodysplastic syndromes.

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The US Food and Drug Administration has new guidelines that enable some gene and cell therapies to undergo expedited review, according to the New York Times.

Using gene drives to control invasive species might be too risky, an initial advocate of the approach says.

In Science this week: intellectual property experts argue patent battles such as the one over CRISPR are wasteful, and more.

Researchers have grown tumors in 3D cell cultures to better understand cancer, the Economist reports.