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myelodysplastic syndrome

WUSTL Expands Patient Pool for WGS Cancer Test After CMS Coverage Milestone
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The high-coverage whole-genome assay is covered for patients with myeloid neoplasms, including acute myeloid leukemia and myelodysplastic syndrome.

Optical Genome Mapping Gains Momentum for Clinical Applications in Hematologic Disorders
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MD Anderson Cancer Center researchers demonstrated the prognostication utility of optical genome mapping in myelodysplastic syndromes patients.

Whole-Genome Sequencing Could Replace Cytogenetics in Assessing AML, Myelodysplastic Syndromes

The researchers found that sequencing was accurate and could even detect chromosomal changes missed by cytogenetics at almost a similar price.

Clinicians Face New Intervention Questions as Clonal Hematopoiesis Mutation Data Evolves
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Increased incidental detection of clonal hematopoiesis and new considerations for mutations in myelodysplastic precursors herald improved precision medicine strategies.

MSK Clonal Hematopoiesis Clinic Aims to Drive New Strategies for Cancer Risk Assessment, Prevention
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The program is in its third year monitoring individuals with these mutations to try to detect disease early, understand their risk, and develop preventive treatments.

Jul 10, 2020

Study Spells Out Immune, Genomic, Epigenomic Interactions in Hematological Malignancies

Aug 12, 2019

Mission Bio, Onconova Therapeutics Sign Cancer Therapy Research Partnership

Aug 8, 2019

Dominant-Negative Effect Detected for Missense TP53 Mutations in Myeloid Cancers

Jul 17, 2019

Cancer Drug Discovery Firm Notable Nabs $40M in Series B Funding Round

Jan 3, 2019

Tumor Sequencing May Pick Up Mutations Caused by Coexistent Blood Disorder

Sep 13, 2018

Myelodysplastic Syndrome Progression Informed by Post-Treatment Mutation Sequencing

Aug 22, 2018

AMP Report Recommends Genes for Chronic Myeloid Neoplasm Sequencing Panels

Feb 9, 2017

Myelodysplastic Syndrome Mutations Offer Prognostic Hints for Stem Cell Transplant Patients

Aug 17, 2016

Cancer Genetics Receives NY State Approval for NGS-Based Cancer Panel

Jun 8, 2016

DNA Sequencing Illuminates 11 Genetic Subtypes of AML
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Jul 2, 2015

Sequencing Offers Clues to Clonal Evolution in Aplastic Anemia

Nov 19, 2014

Dana-Farber, Brigham and Women's Develop NGS Panel for Rapid Diagnosis of Hematologic Cancers
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Nov 5, 2014

NHLBI Awards $7.3M Contract to Moffitt, M2Gen to Coordinate Lab, Biorepository for MDS Study

Oct 13, 2014

Cancer Genetics, Columbia Researchers Collaborate on MDS Biomarkers

Sep 10, 2013

EU Blueprint Effort to Fund Epigenetic Biomarker Projects

Jun 25, 2012

RainDance, MLL Collaborate on Leukemia Panel

Jul 27, 2011

Sequencing/Genotyping Combination Yields Somatic Mutations with Prognostic and Dx Potential in MDS
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Oct 15, 2010

Stanford Researchers Use Nano-Immunoassay to Study Protein Phosphoisoforms Related to Cancer
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Breaking News
The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.