In Cell this week: regulatory changes in pancreatic cancer, metabolic shifts in Alzheimer's disease, and more.
In Science this week: two proteins may help treat muscular dystrophy, and more.
In Science this week: epigenetic memory of environmental changes in roundworms, and more.
Incorporating splicing and other clues from muscle transcripts, researchers reached diagnoses in cases that were inconclusive after sequencing alone.
Exonics will use the funding to advance preclinical research from UT-Southwestern researcher Eric Olson on genome editing of DMD mutations in a mouse model.
UT-SWMC researcher Eric Olson will study dystrophin produced with CRISPR/Cas9 genome editing in a mouse model, as well as off-target effects.
While gain-of-function mutations lead to congenital arhinia, inactivating mutations lead to an adult-onset muscular dystrophy, the researchers reported.
The company's Irys genome mapping technology provides researchers with a non-sequencing-based tool that is essential for studying structural variation.
The grant from the California Institute of Regenerative Medicine will fund research on two approaches to DMD gene therapy using CRISPR/Cas9.
The agreement gives CRISPR Therapeutics access to a technology to create skeletal muscle stem cells for use in research on Duchenne Muscular Dystrophy.
New Mexico is re-doing its proposed science education standards after criticism, the Associated Press reports.
Agbio executives say gene editing will speed up breeding efforts, according to the Wall Street Journal.
La Trobe University's Jenny Graves has won the $250,000 Prime Minister's Prize for Science, the Guardian reports.
In Cell this week: post-treatment changes to melanoma genome, multi-omics analysis of muscle-invasive bladder cancer, and more.