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multiple myeloma

Caris will exclusively offer Signal's Myeloma Prognostic Risk Signature, or MyPRS, test to community-based hematologists and medical oncologists across the US.

Signal will use its genomic testing platform in a multiple myeloma research program being conducted by Array BioPharma.

The company will use part of the €1 million award to investigate biomarkers that will aid in determining which patients are the best candidates for treatment with its MOR202 antibody program, a company official said.

The company said that the protein's expression profile indicates that it might also be useful as a diagnostic and prognostic marker for multiple myeloma.

The results represent the first findings for the MMRC Genomics Initiative, which kicked off last year and aims to initially sequence 50 tumors from patients, and then sequence relevant targets in 200 more samples.

Researchers involved in the Multiple Myeloma Research Consortium Genomics Initiative reported on their initial sequence and copy number analyses of multiple myeloma genomes at the American Association for Cancer Research annual meeting this week.

The initiative, which involves the Broad Institute and the Translational Genomics Research Institute, aims to comprehensively analyze the genomes of 250 multiple myeloma samples. MMRF said this spring that as part of the project, the Broad would sequence the genomes of at least 50 of the tumors.

The firm will use the undisclosed amount to optimize the protocols for its genomic-selection application and to start building a sales and marketing force that "will become more visible in the second half of this year," CEO Fred Dom said.

The study suggests it is "unlikely" that patents protecting biomedical inventions "will ever be licensed" if they have remained unlicensed for more than eight years since their priority patent application was filed.

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Three genetic testing companies form a coalition to influence how Congress considers genetic privacy, The Hill reports.

University of California, San Diego researchers investigate how skin care products influence the skin microbiome, Scientific American reports.

The Wall Street Journal examines billing codes used by uBiome.

In PNAS this week: links between lung adenocarcinoma and lncRNA, algorithm to impute and cluster Hi-C interaction profiles from single cells, and more.