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The test is designed to replace gel electrophoresis assays currently used for measuring M-proteins, biomarkers for plasma cell diseases such as multiple myeloma.
The consortium aims to profile up to 800 multiple myeloma patient samples using the Affymetrix platform with a goal of developing a list of predictive biomarkers.
The partners said they will use genetic sequencing and a combination therapy to determine predictors of sustained minimal residual disease negativity.
The partners will perform genomic sequencing on multiple myeloma patients in order to generate data that can help guide personalized treatments.
In Nucleic Acids Research this week: competitive endogenous RNAs, transcriptomic and proteomic analysis of Plasmodium falciparum, and more.
The UPenn-led study proposal calls for editing three genes in autologous T cells with CRISPR and includes preliminary data for on- and off-target editing.
The company said sales of its MyPRS test for myeloma risk increased during the quarter, but full-year 2015 revenues fell because of increased R&D costs.
Researchers identified a germline variant on chromosome 6 that corresponded to overall survival times in multiple myeloma patients from four study cohorts.
The study will evaluate Signal's MyPRS test for stratifying patients at risk of developing symptomatic multiple myeloma.
The genetic test determines risk levels and prognosis for patients with multiple myeloma based on the SKY92 gene signature.
Nature News reports that genomics is being applied to trace and try to prevent additional COVID-19 waves.
Rady's Children Hospital and San Diego County are teaming up to test pediatric patients and their families for COVID-19 to gauge the spread of the virus locally, according to the San Diego Union-Tribune.
Wildlife managers aim to boost the genetic diversity of Mexican gray wolves by placing captive-born foster pups into packs with similarly aged wild pups, the Mercury News reports.
In Science this week: Genetic Probability tool identifies likely diagnoses in 45 percent of inflammatory arthritis cases, and more.